Minh Tam Tran, Quoc Hung Nguyen, Xinguang Cui, Kum Ju Chae, Sujeong Kim, Ji-Seung Yoo, Sanghun Choi
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引用次数: 0
Abstract
Cement dust is a primary contributor to air pollution and is responsible for causing numerous respiratory diseases. The impact of cement dust exposure on the respiratory health of residents is increasing owing to the demand for construction associated with urbanization. Long-term inhalation of cement dust leads to a reduction in lung function, alterations in airway structure, increased inhalation and exhalation resistance, and heightened work of breath. In this study, we investigated the effects of cement dust exposure on lung function based on the pulmonary function test (PFT) and one-dimensional computational fluid dynamics (1D CFD). Statistical tests were performed to address the disparity of airway function between healthy and cement dust-exposed participants. The percent predicted values of forced vital capacity percent (FVC%) and forced expiratory volume in 1 s (FEV1%) were found to be decreased in the group of dust-exposed participants. An elevation of regional pressure variation was found in cement dust-exposed airways during both inhalation and exhalation that was associated with alternations of airway structural features therein. The 1D CFD model is beneficial for a cost-effective estimation of airway regional pressure and provides valuable insights for more precise diagnosis and treatment planning in individuals exposed to cement dust.
期刊介绍:
The Journal of Biomechanics publishes reports of original and substantial findings using the principles of mechanics to explore biological problems. Analytical, as well as experimental papers may be submitted, and the journal accepts original articles, surveys and perspective articles (usually by Editorial invitation only), book reviews and letters to the Editor. The criteria for acceptance of manuscripts include excellence, novelty, significance, clarity, conciseness and interest to the readership.
Papers published in the journal may cover a wide range of topics in biomechanics, including, but not limited to:
-Fundamental Topics - Biomechanics of the musculoskeletal, cardiovascular, and respiratory systems, mechanics of hard and soft tissues, biofluid mechanics, mechanics of prostheses and implant-tissue interfaces, mechanics of cells.
-Cardiovascular and Respiratory Biomechanics - Mechanics of blood-flow, air-flow, mechanics of the soft tissues, flow-tissue or flow-prosthesis interactions.
-Cell Biomechanics - Biomechanic analyses of cells, membranes and sub-cellular structures; the relationship of the mechanical environment to cell and tissue response.
-Dental Biomechanics - Design and analysis of dental tissues and prostheses, mechanics of chewing.
-Functional Tissue Engineering - The role of biomechanical factors in engineered tissue replacements and regenerative medicine.
-Injury Biomechanics - Mechanics of impact and trauma, dynamics of man-machine interaction.
-Molecular Biomechanics - Mechanical analyses of biomolecules.
-Orthopedic Biomechanics - Mechanics of fracture and fracture fixation, mechanics of implants and implant fixation, mechanics of bones and joints, wear of natural and artificial joints.
-Rehabilitation Biomechanics - Analyses of gait, mechanics of prosthetics and orthotics.
-Sports Biomechanics - Mechanical analyses of sports performance.