Vladeta Ajdacic-Gross, Ana Buadze, En-Young N Wagner, Mario Müller, Erich Seifritz, Setareh Ranjbar, Jennifer Glaus, Enrique Castelao, Marie-Pierre F Strippoli, Caroline L Vandeleur, Martin Preisig, Roland von Känel
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引用次数: 0
Abstract
Previous research has unveiled an intriguing positive association between the AB blood group and mental disorders in general. In this study, we compared ABO blood groups with five major groups of mental disorders to attain a higher level of specificity. The analyses were conducted using data from the CoLaus|PsyCoLaus study (N=5111). They revealed that the AB blood group exhibited a positive association with both neurodevelopmental disorders (RR 2.29, CI 1.38-3.82) and substance use disorders (RR 2.25, CI 1.38-3.65) after adjusting for sex and childhood adversities. These associations could be replicated with respect to the familial aggregation of neurodevelopmental and substance use disorders. Large databases are needed to achieve more detailed results related to specific disorders.
之前的研究已经揭示了AB型血和精神疾病之间有趣的正相关关系。在这项研究中，我们将ABO血型与五种主要的精神障碍组进行比较，以获得更高的特异性。分析使用CoLaus|PsyCoLaus研究的数据（N=5111）。他们发现，在调整性别和童年逆境后，AB血型与神经发育障碍（RR 2.29, CI 1.38-3.82）和物质使用障碍（RR 2.25, CI 1.38-3.65）呈正相关。这些关联可以在神经发育障碍和物质使用障碍的家族聚集性方面得到复制。需要大型数据库来获得与特定疾病有关的更详细的结果。
期刊介绍：
The Journal of Blood Medicine is an international, peer-reviewed, open access, online journal publishing laboratory, experimental and clinical aspects of all topics pertaining to blood based medicine including but not limited to: Transfusion Medicine (blood components, stem cell transplantation, apheresis, gene based therapeutics), Blood collection, Donor issues, Transmittable diseases, and Blood banking logistics, Immunohematology, Artificial and alternative blood based therapeutics, Hematology including disorders/pathology related to leukocytes/immunology, red cells, platelets and hemostasis, Biotechnology/nanotechnology of blood related medicine, Legal aspects of blood medicine, Historical perspectives. Original research, short reports, reviews, case reports and commentaries are invited.
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