Evaluation of a Point-of-Care-Viscoelastic Coagulation Device in Hispaniolan Amazon Parrots (Amazona ventralis).

IF 0.6 4区 农林科学 Q3 VETERINARY SCIENCES
Laken Russell, Thomas N Tully, M Ryan Smith, Mark A Mitchell
{"title":"Evaluation of a Point-of-Care-Viscoelastic Coagulation Device in Hispaniolan Amazon Parrots (<i>Amazona ventralis</i>).","authors":"Laken Russell, Thomas N Tully, M Ryan Smith, Mark A Mitchell","doi":"10.1647/AVIANMS-D-23-00050","DOIUrl":null,"url":null,"abstract":"<p><p>Viscoelastic testing evaluates the formation and lysis of a clot over time, allowing more complete assessment of patient hemostasis in real time, whereas traditional tests, such as prothrombin time and partial thromboplastin time, only measure coagulation factor function. Patient-side viscoelastic coagulation monitors are easy to use, portable, and provide faster turnaround time than commercial laboratories. Viscoelastic testing requires only 0.2 mL of blood and is useful in diagnosing and treating hemostatic disorders. Currently, there is no standardized coagulation testing method across bird species. In this cross-sectional study, a viscoelastic coagulation device, the Entegrion Viscoelastic Coagulation Monitor-Vet (VCM-Vet), was evaluated. Blood samples were obtained from 26 Hispaniolan Amazon parrots (HAPs) (<i>Amazona ventralis</i>) under manual restraint. Results were recorded on the device as graphical output with quantitative viscoelastic measurements. Results were reported using standard rotational thromboelastometry terminology, including clotting time, clot formation time, alpha angle, maximum clot firmness, clot firmness amplitude at 10 and 20 minutes after clot formation, and clot lysis at 30 and 45 minutes. The median clotting time was 463 seconds (reference interval: 56-1635 seconds), the mean clot formation time was 704.7 seconds (reference interval: 172-1697 seconds), the mean alpha angle was 27.3 (reference interval: 7-60), and the mean maximum clot firmness was 15.4 (reference interval: 7-25). Statistical analysis found that all parameters were normally distributed aside from clotting time in seconds. There was no appreciable breakdown of the clot during the 60-minute device runtime, and there was no significant difference in any parameter based on sex. The VCM-Vet produced clotting times for this population of HAPs and enabled the creation of reference intervals. Based on our findings, the VCM-Vet can be used to assess clot potential in HAPs and possibly other avian species.</p>","PeriodicalId":15102,"journal":{"name":"Journal of Avian Medicine and Surgery","volume":"38 4","pages":"188-196"},"PeriodicalIF":0.6000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Avian Medicine and Surgery","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1647/AVIANMS-D-23-00050","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Viscoelastic testing evaluates the formation and lysis of a clot over time, allowing more complete assessment of patient hemostasis in real time, whereas traditional tests, such as prothrombin time and partial thromboplastin time, only measure coagulation factor function. Patient-side viscoelastic coagulation monitors are easy to use, portable, and provide faster turnaround time than commercial laboratories. Viscoelastic testing requires only 0.2 mL of blood and is useful in diagnosing and treating hemostatic disorders. Currently, there is no standardized coagulation testing method across bird species. In this cross-sectional study, a viscoelastic coagulation device, the Entegrion Viscoelastic Coagulation Monitor-Vet (VCM-Vet), was evaluated. Blood samples were obtained from 26 Hispaniolan Amazon parrots (HAPs) (Amazona ventralis) under manual restraint. Results were recorded on the device as graphical output with quantitative viscoelastic measurements. Results were reported using standard rotational thromboelastometry terminology, including clotting time, clot formation time, alpha angle, maximum clot firmness, clot firmness amplitude at 10 and 20 minutes after clot formation, and clot lysis at 30 and 45 minutes. The median clotting time was 463 seconds (reference interval: 56-1635 seconds), the mean clot formation time was 704.7 seconds (reference interval: 172-1697 seconds), the mean alpha angle was 27.3 (reference interval: 7-60), and the mean maximum clot firmness was 15.4 (reference interval: 7-25). Statistical analysis found that all parameters were normally distributed aside from clotting time in seconds. There was no appreciable breakdown of the clot during the 60-minute device runtime, and there was no significant difference in any parameter based on sex. The VCM-Vet produced clotting times for this population of HAPs and enabled the creation of reference intervals. Based on our findings, the VCM-Vet can be used to assess clot potential in HAPs and possibly other avian species.

一种即时护理粘弹性凝血装置在西班牙亚马孙鹦鹉(腹侧亚马孙鹦鹉)中的应用。
粘弹性测试评估随着时间的推移凝块的形成和溶解,允许更完整的实时评估患者止血,而传统的测试,如凝血酶原时间和部分凝血活酶时间,只能测量凝血因子功能。患者侧粘弹性凝血监测仪易于使用,便携,并提供比商业实验室更快的周转时间。粘弹性试验只需要0.2 mL血液,可用于诊断和治疗止血疾病。目前,还没有统一的跨鸟类凝血检测方法。在这项横断面研究中,对粘弹性凝血装置integrion粘弹性凝血监测- vet (VCM-Vet)进行了评估。在人工约束下采集了26只亚马逊鹦鹉的血液样本。结果记录在设备上的图形输出与定量粘弹性测量。结果报告使用标准的旋转血栓弹性测量术语,包括凝血时间,凝块形成时间,α角,最大凝块硬度,凝块形成后10和20分钟的凝块硬度振幅,以及30和45分钟的凝块溶解。平均凝血时间为463秒(参考区间:56 ~ 1635秒),平均凝块形成时间为704.7秒(参考区间:172 ~ 1697秒),平均alpha角为27.3(参考区间:7 ~ 60),平均最大凝块硬度为15.4(参考区间:7 ~ 25)。统计分析发现,除凝血时间(以秒为单位)外,其他参数均为正态分布。在60分钟的设备运行期间,没有明显的血栓破裂,并且基于性别的任何参数都没有显着差异。VCM-Vet生成了这群hap的凝血时间,并创建了参考区间。基于我们的研究结果,VCM-Vet可用于评估HAPs和其他鸟类的凝块潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Avian Medicine and Surgery
Journal of Avian Medicine and Surgery 农林科学-兽医学
CiteScore
0.90
自引率
0.00%
发文量
52
审稿时长
>36 weeks
期刊介绍: The Journal of Avian Medicine and Surgery is an international journal of the medicine and surgery of both captive and wild birds. Published materials include scientific articles, case reports, editorials, abstracts, new research, and book reviews.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信