{"title":"Intraindividual correlations between nocturnal urination frequency and sleep blood pressure: the Nagahama Study.","authors":"Yasuharu Tabara, Takeshi Matsumoto, Kimihiko Murase, Takahisa Kawaguchi, Kazuya Setoh, Tomoko Wakamura, Toyohiro Hirai, Kazuo Chin, Fumihiko Matsuda","doi":"10.1038/s41440-024-02085-9","DOIUrl":null,"url":null,"abstract":"<p><p>Nocturnal urination frequency is associated with sleep blood pressure (BP). However, it was uncertain to what extent the sleep BP increases within individuals with each increase in the number of nocturnal urination. We calculated intraindividual differences in sleep BP between nights with different urination frequencies to clarify their relationship. We enrolled 2418 community residents (mean age, 61.1 years). Participants wore a cuff on the upper arm when sleeping that automatically measured BP at fixed times during a 1-week period. The frequency of nocturnal urination was recorded in a sleep diary by the study participants. Sleep systolic BP increased with increased nocturnal urination frequency (0 time vs. 1 time, Δ2.1 mmHg, P < 0.001; 1 time vs. 2 times, Δ1.8 mmHg, P < 0.001; 2 times vs. ≥3 times, Δ1.4 mmHg, P = 0.012), and a similar association was observed for sleep diastolic BP. These associations were independent of age, the use of antihypertensive drugs reduced renal function, and the presence of sleep-disordered breathing. Sleep BP in participants who experienced nocturnal urination 0, 1, and 2 times during the 1-week measurement period showed a linear increase with the frequency of urination (0 time vs. 2 times: systolic BP, Δ4.7 mmHg; diastolic BP, Δ3.1 mmHg; P < 0.001). There was an intraindividual correlation between nocturnal urination frequency and sleep BP. These correlations were independent of baseline BP and participants' clinical backgrounds. Nocturnal urination frequency may be an indicator of individuals who require detailed ambulatory BP measurement.</p>","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3000,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hypertension Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41440-024-02085-9","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 0
Abstract
Nocturnal urination frequency is associated with sleep blood pressure (BP). However, it was uncertain to what extent the sleep BP increases within individuals with each increase in the number of nocturnal urination. We calculated intraindividual differences in sleep BP between nights with different urination frequencies to clarify their relationship. We enrolled 2418 community residents (mean age, 61.1 years). Participants wore a cuff on the upper arm when sleeping that automatically measured BP at fixed times during a 1-week period. The frequency of nocturnal urination was recorded in a sleep diary by the study participants. Sleep systolic BP increased with increased nocturnal urination frequency (0 time vs. 1 time, Δ2.1 mmHg, P < 0.001; 1 time vs. 2 times, Δ1.8 mmHg, P < 0.001; 2 times vs. ≥3 times, Δ1.4 mmHg, P = 0.012), and a similar association was observed for sleep diastolic BP. These associations were independent of age, the use of antihypertensive drugs reduced renal function, and the presence of sleep-disordered breathing. Sleep BP in participants who experienced nocturnal urination 0, 1, and 2 times during the 1-week measurement period showed a linear increase with the frequency of urination (0 time vs. 2 times: systolic BP, Δ4.7 mmHg; diastolic BP, Δ3.1 mmHg; P < 0.001). There was an intraindividual correlation between nocturnal urination frequency and sleep BP. These correlations were independent of baseline BP and participants' clinical backgrounds. Nocturnal urination frequency may be an indicator of individuals who require detailed ambulatory BP measurement.
夜间排尿频率与睡眠血压(BP)有关。然而,不确定睡眠血压随着个体夜间排尿次数的增加而增加到什么程度。我们计算了不同排尿频率的夜晚之间睡眠血压的个体差异,以澄清它们之间的关系。我们招募了2418名社区居民(平均年龄61.1岁)。参与者睡觉时在上臂上戴上一个袖带,在一周的时间内固定时间自动测量血压。研究参与者在睡眠日记中记录了夜间排尿的频率。睡眠收缩压随夜间排尿次数增加而升高(0次vs. 1次,Δ2.1 mmHg, P
期刊介绍:
Hypertension Research is the official publication of the Japanese Society of Hypertension. The journal publishes papers reporting original clinical and experimental research that contribute to the advancement of knowledge in the field of hypertension and related cardiovascular diseases. The journal publishes Review Articles, Articles, Correspondence and Comments.