Association Between Coffee Intake and Common Mental Disorders: Insights From Genetic Analysis

IF 4.8 1区医学 Q1 NEUROSCIENCES

CNS Neuroscience & Therapeutics Pub Date : 2025-01-07 DOI:10.1111/cns.70213

Zhiqiang Du, Ying Jiang, Yuan Shen, Qin Zhou, Peng Gong, Haohao Zhu

引用次数: 0

Abstract

The study found a significant causal relationship between coffee intake and obsessive-compulsive disorder, showing a negative correlation. There was no causal relationship between coffee intake and other mental disorders. The sensitivity analysis test found no pleiotropy affecting the results, and no single nucleotide polymorphism had a major impact on the robustness of the results, indicating that the results are stable and reliable.

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咖啡摄入量与常见精神疾病之间的关系：来自基因分析的见解。

研究发现，咖啡摄入量与强迫症之间存在显著的因果关系，呈负相关。咖啡摄入和其他精神疾病之间没有因果关系。敏感性分析检验未发现多效性影响结果，单核苷酸多态性未对结果的稳健性产生重大影响，说明结果稳定可靠。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

CNS Neuroscience & Therapeutics 医学-神经科学

CiteScore

7.30

自引率

12.70%

发文量

240

审稿时长

2 months

期刊介绍： CNS Neuroscience & Therapeutics provides a medium for rapid publication of original clinical, experimental, and translational research papers, timely reviews and reports of novel findings of therapeutic relevance to the central nervous system, as well as papers related to clinical pharmacology, drug development and novel methodologies for drug evaluation. The journal focuses on neurological and psychiatric diseases such as stroke, Parkinson’s disease, Alzheimer’s disease, depression, schizophrenia, epilepsy, and drug abuse.