A. S. Baikin, E. O. Nasakina, A. A. Mel’nikova, M. A. Kaplan, K. V. Sergienko, S. V. Konushkin, A. G. Kolmakov, M. A. Sevost’yanov
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Abstract
The preliminary results of studying the efficiency of using the siloxane low-molecular-weight SKTN-A rubber as a matrix for a thin-film drug coating of implantable stents are presented. A porous film structure is formed by the introduction of intermediate (removable) fillers, such as ethanol, sodium hydrocarbonate, and high-molecular-weight chitosan. The ultimate tensile strength and the relative elongation of the prepared films are studied. The strength of the films formed using ethanol is found to be nearly analogous to that of pure siloxane, but their relative elongation is lower by 10%. The use of sodium hydrocarbonate makes it possible to enhance the strength of the films by 37% (to 0.22 MPa), and the relative elongation increases to 93%. When chitosan is used, the strength of the films increases almost twofold (to 0.28 MPa) and their plasticity is similar to that of pure siloxane and amounts to approximately 40%.
期刊介绍：
Russian Metallurgy (Metally) publishes results of original experimental and theoretical research in the form of reviews and regular articles devoted to topical problems of metallurgy, physical metallurgy, and treatment of ferrous, nonferrous, rare, and other metals and alloys, intermetallic compounds, and metallic composite materials. The journal focuses on physicochemical properties of metallurgical materials (ores, slags, matters, and melts of metals and alloys); physicochemical processes (thermodynamics and kinetics of pyrometallurgical, hydrometallurgical, electrochemical, and other processes); theoretical metallurgy; metal forming; thermoplastic and thermochemical treatment; computation and experimental determination of phase diagrams and thermokinetic diagrams; mechanisms and kinetics of phase transitions in metallic materials; relations between the chemical composition, phase and structural states of materials and their physicochemical and service properties; interaction between metallic materials and external media; and effects of radiation on these materials.
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