Human embryo editing against disease is unsafe and unproven — despite rosy predictions

IF 48.5 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Nature Pub Date : 2025-01-08 DOI:10.1038/d41586-024-04105-7

Shai Carmi, Henry T. Greely, Kevin J. Mitchell

引用次数: 0

Abstract

Mathematical modelling suggests that it is theoretically possible to reduce risk of common diseases using heritable genome editing. Scientists argue that the technology involves considerable risk and uncertain benefits. Pitfalls of heritable genome editing undermine theoretical benefits.

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尽管有乐观的预测，但针对疾病的人类胚胎编辑是不安全和未经证实的

可遗传基因组编辑的缺陷削弱了理论上的好处。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature 综合性期刊-综合性期刊

CiteScore

90.00

自引率

1.20%

发文量

3652

审稿时长

3 months

期刊介绍： Nature is a prestigious international journal that publishes peer-reviewed research in various scientific and technological fields. The selection of articles is based on criteria such as originality, importance, interdisciplinary relevance, timeliness, accessibility, elegance, and surprising conclusions. In addition to showcasing significant scientific advances, Nature delivers rapid, authoritative, insightful news, and interpretation of current and upcoming trends impacting science, scientists, and the broader public. The journal serves a dual purpose: firstly, to promptly share noteworthy scientific advances and foster discussions among scientists, and secondly, to ensure the swift dissemination of scientific results globally, emphasizing their significance for knowledge, culture, and daily life.