Acute and chronic detrimental effects induced by short-chain chlorinated paraffins in the marine mysid Neomysis awatschensis

Abstract

To determine the potentially detrimental impacts of short-chain chlorinated paraffins (SCCPs), we conducted assessments of acute effects on 96-h survival rate and biochemical markers, as well as chronic and multigenerational impacts on growth and reproduction over three generations in the marine mysid, Neomysis awatschensis. Dose-dependent increase of mortality was measured in both juvenile and adult mysids for 96 h. Exposure to the LC10 value (derived from the 96-h acute toxicity value) significantly reduced feeding activity in juveniles, accompanied by a significant elevation in oxidative stress and a reduction in acetylcholinesterase activity. When juvenile and adult mysids were exposed to 1/10 of the NOEC and NOEC values for four weeks, mortality significantly increased in juveniles. Furthermore, mysids subjected to constant exposure to 1/10 of the NOEC and NOEC values across three generations, F0–F2, displayed more pronounced growth retardation, an extended intermolt duration, and a reduced rate of reproduction. These results collectively indicate that even sublethal concentrations of SCCPs can have harmful effects on the health status of mysid populations when they are consistently exposed.