Dancing Glycoproteins: Memory Pattern Formation by Protein Folding through Hydrogen Bonding.

IF 3.5 4区 医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Atta-Ur-Rahman
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引用次数: 0

Abstract

A considerable amount of work has been carried out on the biology of learning and memory acquisition, and retention [1-6]; however, little is known regarding how the information is written in the brain [7-9]. It is notable that in the Neuron Theory postulated by Santiago Ramón y Cajal [10], neurons were conceived to form a contiguous instead of a continuous structure. They were physically separated but could function through their connections by synapses [11]. The electric impulses are initiated by the presynaptic neurons and transmitted through a synapse to the postsynaptic neuron, and they then travel toward the axon. A considerable amount of work on the molecular and cellular mechanisms has been undertaken in this fast-evolving field [11-16].

跳舞的糖蛋白:通过氢键蛋白质折叠形成的记忆模式。
在学习和记忆获得和保持的生物学方面已经开展了大量的工作[1-6];然而,关于信息是如何在大脑中写入的,我们知之甚少[7-9]。值得注意的是,在Santiago Ramón y Cajal[10]假设的神经元理论中,神经元被认为是一个连续的结构,而不是一个连续的结构。它们在物理上是分开的,但可以通过突触[11]的连接来发挥作用。电脉冲由突触前神经元发起,通过突触传递到突触后神经元,然后向轴突移动。在这一快速发展的领域,已经开展了大量关于分子和细胞机制的工作[11-16]。
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来源期刊
Current medicinal chemistry
Current medicinal chemistry 医学-生化与分子生物学
CiteScore
8.60
自引率
2.40%
发文量
468
审稿时长
3 months
期刊介绍: Aims & Scope Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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