Optimization of subcritical water extraction parameters of phlorotannins from brown alga (Ecklonia stolonifera): Bipotentialities and possible applications

IF 3.4 3区工程技术 Q2 CHEMISTRY, PHYSICAL

Journal of Supercritical Fluids Pub Date : 2024-12-26 DOI:10.1016/j.supflu.2024.106502

Ye-Seul Park , Vikash Chandra Roy , Jin-Seok Park , Wei Zhang , Byung-Soo Chun

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Abstract

The study aimed to identify the optimal subcritical water extraction (SWE) parameters for phlorotannin (marine polyphenols) from Ecklonia stolonifera using response surface methodology (RSM). The reaction temperature, time, and the solid-to-solvent ratio were optimized, and the best extraction conditions were 198.5°C, 36.21 min, and 12.23 g/mL, respectively. Under optimal conditions, the total phlorotannin content (TPC) was 50.01 ± 0.12 mg phloroglucinol/g dried seaweed powder. The results indicated that the E. stolonifera extract showed substantial ABTS⁺, DPPH radical scavenging, and FRAP activities (70.94 ± 0.15, 60.03 ± 0.35, and 29.45 ± 0.39 mg Trolox equivalent/g dried seaweed powder, respectively). The resulting extract exhibited potential antihypertensive (95.87 % ± 0.01 %), α-glucosidase inhibitory (69.29 % ± 1.83 %), and anti-inflammatory (68.55 % ± 0.98 %) activity compared with the positive control. In conclusion, this study underscores the immense potential of E. stolonifera as a valuable nutraceutical material when prepared by the SWE method.

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棕藻绿皮单宁亚临界水提取工艺的优化：双电位及应用前景

本研究旨在利用响应面法（RSM）确定亚临界水萃取法（SWE）提取匍匐花中苯酞酸（海洋多酚）的最佳工艺参数。对反应温度、时间和料液比进行优化，最佳提取条件分别为198.5℃、36.21 min和12.23 g/mL。在最佳条件下，总间苯三酚含量（TPC）为50.01 ± 0.12 mg /g干海藻粉。结果表明，匍匐花提取物具有较强的ABTS+、DPPH自由基清除和FRAP活性（分别为70.94 ± 0.15、60.03 ± 0.35和29.45 ± 0.39 mg Trolox当量/g干海藻粉）。结果提取表现出潜在的抗高血压(95.87 % ±0.01  %),α葡糖苷酶抑制(69.29 % ±1.83  %),和抗炎(68.55 % ±0.98  %)活动较积极的控制。综上所述，本研究强调了用SWE方法制备的栗白草作为一种有价值的营养保健材料的巨大潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Supercritical Fluids 工程技术-工程：化工

CiteScore

7.60

自引率

10.30%

发文量

236

审稿时长

56 days

期刊介绍： The Journal of Supercritical Fluids is an international journal devoted to the fundamental and applied aspects of supercritical fluids and processes. Its aim is to provide a focused platform for academic and industrial researchers to report their findings and to have ready access to the advances in this rapidly growing field. Its coverage is multidisciplinary and includes both basic and applied topics. Thermodynamics and phase equilibria, reaction kinetics and rate processes, thermal and transport properties, and all topics related to processing such as separations (extraction, fractionation, purification, chromatography) nucleation and impregnation are within the scope. Accounts of specific engineering applications such as those encountered in food, fuel, natural products, minerals, pharmaceuticals and polymer industries are included. Topics related to high pressure equipment design, analytical techniques, sensors, and process control methodologies are also within the scope of the journal.