Ethylene glycol toxicosis in 39 sport horses following ingestion of contaminated water: A case report

IF 1.3 3区农林科学 Q2 VETERINARY SCIENCES

Journal of Equine Veterinary Science Pub Date : 2025-02-01 DOI:10.1016/j.jevs.2025.105343

Zs. Daradics , D. Bungărdean , A.F. Lupșan , M. Popescu , O. Bulmez , V. Ciulu-Angelescu , V.F. Chelaru , I. Morar , M. Mircean , C. Cătoi , M.A. Tripon , C.M. Crecan

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引用次数: 0

Abstract

Ethylene glycol toxicosis is a common occurrence in dogs and cats but has been reported in other species as well. Up to date, only one case of ethylene glycol toxicosis has been described in horses, and specific guidelines for treating ethylene glycol intoxication in this species are not available. Here we describe the case of 39 sport horses that ingested water contaminated with ethylene glycol. The main clinical sign was apathy, but more severely affected individuals also developed abdominal pain and laminitis. Treatment was initiated around 24 h after the exposure, using ethanol as an antidote, which was administered initially through a nasogastric tube and subsequently via perfusion. Five horses required hospitalization, but all 39 horses recovered. Based on biochemical measurements performed at different timepoints, we proposed several markers that can be used to determine the need for specialized care early on during the treatment.

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39匹运动马饮用受污染的水后乙二醇中毒：1例报告。

乙二醇中毒在狗和猫中很常见，但在其他物种中也有报道。到目前为止，只有一个乙二醇中毒病例已被描述在马，和具体的指导方针治疗乙二醇中毒在这个物种是不可用的。在这里，我们描述了39匹运动马摄入了被乙二醇污染的水的情况。临床表现以冷漠为主，重者可出现腹痛、板炎等症状。暴露后约24小时开始治疗，使用乙醇作为解毒剂，最初通过鼻胃管施用，随后通过灌注施用。5匹马需要住院治疗，但所有39匹马都康复了。根据在不同时间点进行的生化测量，我们提出了几个标记，可用于确定在治疗早期需要专门护理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Equine Veterinary Science 农林科学-兽医学

CiteScore

2.70

自引率

7.70%

发文量

249

审稿时长

77 days

期刊介绍： Journal of Equine Veterinary Science (JEVS) is an international publication designed for the practicing equine veterinarian, equine researcher, and other equine health care specialist. Published monthly, each issue of JEVS includes original research, reviews, case reports, short communications, and clinical techniques from leaders in the equine veterinary field, covering such topics as laminitis, reproduction, infectious disease, parasitology, behavior, podology, internal medicine, surgery and nutrition.