Assessing the impact of magnesium-based nutritional education on lipid profiles in individuals with type 2 diabetes mellitus: a quasi-experimental study.

IF 3.4 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Eram Albajri, Arwa S Almasaudi, Hala H Mosli, Noor A Hakim, Reem O Basaqr, Manal Naseeb
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Abstract

Background: The potential therapeutic role of magnesium (Mg) in type 2 diabetes mellitus (T2DM) remains insufficiently studied despite its known involvement in critical processes like lipid metabolism and insulin sensitivity. This study examines the impact of Mg-focused nutritional education on lipid profile parameters, total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) in T2DM patients.

Methods: Thirty participants with T2DM were recruited for this within-subject experimental study. Participants underwent a three-month dietary intervention focused on increasing the intake of Mg-rich foods through nutritional education. Anthropometric measurements and lipids were assessed at baseline and after the intervention period, with the primary outcome variables including changes in lipid parameters.

Results: The findings showed a significant inverse association between dietary Mg intake and total cholesterol levels (r = - 0.36, p = 0.05). However, other parameters, TG, LDL-C, and HDL-C, were not found to be associated with Mg intake.

Conclusion: The study demonstrated an inverse association between Mg intake and cholesterol level. Providing nutritional education and guidance on incorporating Mg-rich foods into the diet may be a crucial strategy for improving the health and well-being of T2DM patients in Saudi Arabia. The feasibility and practicality of focused nutritional education as an intervention make it a low-cost, scalable, and sustainable approach that can be readily implemented in clinical and community settings. Further studies are needed to explore the long-term impact of dietary Mg interventions on a larger sample with longer education periods.

评估以镁为基础的营养教育对2型糖尿病患者血脂的影响:一项准实验研究
背景:尽管已知镁参与脂质代谢和胰岛素敏感性等关键过程,但其在2型糖尿病(T2DM)中的潜在治疗作用仍未得到充分研究。本研究探讨了以mg为重点的营养教育对T2DM患者血脂参数、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)的影响。方法:招募30名T2DM患者进行受试者内实验研究。参与者接受了为期三个月的饮食干预,重点是通过营养教育增加富含镁的食物的摄入量。在基线和干预期后评估人体测量值和血脂,主要结局变量包括脂质参数的变化。结果:膳食镁摄入量与总胆固醇水平呈显著负相关(r = - 0.36, p = 0.05)。然而,其他参数,TG, LDL-C和HDL-C,没有发现与Mg摄入量相关。结论:研究表明镁摄入量与胆固醇水平呈负相关。提供营养教育和指导,将富含镁的食物纳入饮食中,可能是改善沙特阿拉伯2型糖尿病患者健康和福祉的关键策略。重点营养教育作为一种干预措施的可行性和实用性使其成为一种低成本、可扩展和可持续的方法,可以在临床和社区环境中轻松实施。需要进一步的研究来探索膳食镁干预对更大样本和更长的教育周期的长期影响。
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来源期刊
Diabetology & Metabolic Syndrome
Diabetology & Metabolic Syndrome ENDOCRINOLOGY & METABOLISM-
CiteScore
6.20
自引率
0.00%
发文量
170
审稿时长
7.5 months
期刊介绍: Diabetology & Metabolic Syndrome publishes articles on all aspects of the pathophysiology of diabetes and metabolic syndrome. By publishing original material exploring any area of laboratory, animal or clinical research into diabetes and metabolic syndrome, the journal offers a high-visibility forum for new insights and discussions into the issues of importance to the relevant community.
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