The importance of inflammation in atrial fibrillation recurrence in patients with atrial fibrillation treated with Cryo balloon ablation

Q3 Medicine

Indian Pacing and Electrophysiology Journal Pub Date : 2025-01-01 DOI:10.1016/j.ipej.2024.12.005

Deniz Elcik , Aydin Tuncay , Mustafa Fehmi Bireciklioglu , Mehmet Tugrul İnanc

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引用次数: 0

Abstract

Aim/background

Although atrial fibrillation is the most common rhythm problem, the results of treatment to restore sinus rhythm are still not satisfactory. Nearly half of patients undergoing ablation relapse within one year. Therefore, triggered activities may not be the only cause. Inflammation is quite common in AF. In this study, we investigated the effect of PIV, an inflammatory marker, on recurrence.

Methods

A total of 157 patients who underwent ablation with cryo balloon were included in the study. One-year follow-up was evaluated for causes of recurrence.

Results

When the inflammatory parameters between the two groups are analyzed, CRP (5.9 [5.0–6.9] vs 9.7 [7.6–11.9], p < 0.001), NL ratio (2.8 [2.5–3.0] vs 6.4 [5.0–6.8], p < 0.001), SII2 (618.5 [557.1–679.9] vs 1798.9 [1305.8–2292.1], p < 0.001), PIV (355.9 [313.4–398.4] vs 1832 [1317.8–2347.1], p < 001) were significantly higher in the AF recurrence group. ROC analysis showed that PIV had the best sensitivity and specificity.

Conclusions

Inflammation has been found to be a cause of AF recurrence and PIV is one of the best markers for this.

查看原文本刊更多论文

低温球囊消融治疗心房颤动患者中炎症在房颤复发中的重要性。

目的/背景虽然心房颤动是最常见的心律问题，但恢复窦性心律的治疗结果仍不令人满意。近一半接受消融术的患者在一年内复发。因此，触发的活动可能不是唯一的原因。炎症在房颤中很常见。在本研究中，我们研究了PIV（一种炎症标志物）对房颤复发的影响。方法选取157例行冷冻球囊消融术的患者作为研究对象。随访1年，评估复发原因。结果两组患者炎症参数比较，CRP (5.9 [5.0-6.9] vs . 9.7 [7.6-11.9], p <；0.001),问比(2.8(2.5 - -3.0)和6.4 (5.0 - -6.8),p & lt;0.001), SII2(618.5(557.1 - -679.9)和1798.9 (1305.8 - -2292.1),p & lt;0.001), PIV(355.9[313.4—-398.4]vs 1832 [1317.8 - -2347.1], p & lt;（001）在AF复发组中明显增高。ROC分析显示PIV具有最佳的敏感性和特异性。结论炎症是房颤复发的原因之一，PIV是房颤复发的最佳标志物之一。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Pacing and Electrophysiology Journal Medicine-Cardiology and Cardiovascular Medicine

CiteScore

2.20

自引率

0.00%

发文量

审稿时长

61 days

期刊介绍： Indian Pacing and Electrophysiology Journal is a peer reviewed online journal devoted to cardiac pacing and electrophysiology. Editorial Advisory Board includes eminent personalities in the field of cardiac pacing and electrophysiology from Asia, Australia, Europe and North America.