The Rise of Type 2 Diabetes in Children and Adolescents: An Emerging Pandemic

IF 4.6 2区 医学 Q1 ENDOCRINOLOGY & METABOLISM
Shiwali Goyal, Vanita Vanita
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引用次数: 0

Abstract

Aim

This review explores the increasing prevalence of Type 2 Diabetes Mellitus (T2DM) in children and adolescents, focusing on its etiology, risk factors, complications, and the importance of early detection and management. It also highlights the need for a multidisciplinary, family-centered approach in managing T2DM in pediatric populations, with an emphasis on nutrition, exercise, and lifestyle interventions.

Materials and Methods

A literature review was conducted using PubMed, Google Scholar, and Scopus to incorporate studies from 2015 to 2024 on T2DM in youths/adolescents/children, focusing on epidemiology, risk factors, and prevention strategies. Studies on Type 1 Diabetes Mellitus (T1DM) or adult populations were excluded.

Results

T2DM is a complex metabolic disorder with various societal, behavioral, environmental, and genetic risk factors. It accounts for one in three new childhood diabetes cases, with rising incidence among American Indian/Alaska Native, Black, and Hispanic/Latino children. The increase in T2DM incidence correlates with growing childhood obesity rates. Early onset significantly raises the risk of complications like retinopathy, nephropathy, neuropathy, cardiovascular diseases, nonalcoholic fatty liver disease, and obstructive sleep apnea. Early detection, screening, and treatment can prevent or delay these complications. A family-centered, multidisciplinary approach is essential for effective management, including lifestyle and behavioral support.

Conclusions

T2DM in children is a growing health concern with severe implications. Early detection and management, including nutrition and exercise counseling, are critical in reducing long-term complications. A multidisciplinary approach is vital for improving outcomes and minimizing morbidity and mortality.

2型糖尿病在儿童和青少年中的发病率上升:一种新兴的流行病。
目的:本综述探讨了儿童和青少年中2型糖尿病(T2DM)日益增加的患病率,重点讨论了其病因、危险因素、并发症以及早期发现和治疗的重要性。它还强调了在儿科人群中管理2型糖尿病需要多学科、以家庭为中心的方法,重点是营养、运动和生活方式干预。材料和方法:通过PubMed、谷歌Scholar和Scopus进行文献综述,纳入2015 - 2024年青少年/青少年/儿童2型糖尿病的研究,重点关注流行病学、危险因素和预防策略。排除1型糖尿病(T1DM)或成人人群的研究。结果:T2DM是一种复杂的代谢性疾病,具有多种社会、行为、环境和遗传危险因素。它占了三分之一的新儿童糖尿病病例,在美国印第安人/阿拉斯加原住民、黑人和西班牙裔/拉丁裔儿童中的发病率不断上升。2型糖尿病发病率的增加与儿童肥胖率的增加有关。早发会显著增加并发症的风险,如视网膜病变、肾病、神经病变、心血管疾病、非酒精性脂肪性肝病和阻塞性睡眠呼吸暂停。早期发现、筛查和治疗可以预防或延缓这些并发症。以家庭为中心的多学科方法对有效管理至关重要,包括生活方式和行为支持。结论:儿童2型糖尿病是一个日益严重的健康问题。早期发现和管理,包括营养和运动咨询,对于减少长期并发症至关重要。多学科方法对于改善结果和尽量减少发病率和死亡率至关重要。
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来源期刊
Diabetes/Metabolism Research and Reviews
Diabetes/Metabolism Research and Reviews 医学-内分泌学与代谢
CiteScore
17.20
自引率
2.50%
发文量
84
审稿时长
4-8 weeks
期刊介绍: Diabetes/Metabolism Research and Reviews is a premier endocrinology and metabolism journal esteemed by clinicians and researchers alike. Encompassing a wide spectrum of topics including diabetes, endocrinology, metabolism, and obesity, the journal eagerly accepts submissions ranging from clinical studies to basic and translational research, as well as reviews exploring historical progress, controversial issues, and prominent opinions in the field. Join us in advancing knowledge and understanding in the realm of diabetes and metabolism.
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