Conditioned Pain Modulation (CPM) Paradigms: Reliability and Relationship With Individual Characteristics.

IF 1.6 4区医学 Q2 NURSING

Pain Management Nursing Pub Date : 2024-12-31 DOI:10.1016/j.pmn.2024.12.001

Antonio Gil-Ugidos, Lara Rubal-Otero, Alberto González-Villar, María Teresa Carrillo-De-la-Peña

{"title":"Conditioned Pain Modulation (CPM) Paradigms: Reliability and Relationship With Individual Characteristics.","authors":"Antonio Gil-Ugidos, Lara Rubal-Otero, Alberto González-Villar, María Teresa Carrillo-De-la-Peña","doi":"10.1016/j.pmn.2024.12.001","DOIUrl":null,"url":null,"abstract":"Purpose: Conditioned Pain Modulation (CPM) is a useful tool for testing the functionality of endogenous pain modulation. However, inconsistent results have been obtained in clinical populations, possibly due to the wide variety of CPM protocols used and the influence of demographic and psychological characteristics of the individuals assessed.Methods: We tested the sensitivity and reliability of four commonly used CPM paradigms in a sample of 58 healthy participants. We also checked how these measures were related to Temporal Summation of Second Pain (TSSP), sociodemographic (age and sex) and psychological variables (anxiety and stress).Results: CPM results were influenced by the test stimulus used, with tests using pain pressure threshold (PPT) obtaining a greater number of responders (over 65%) and being the most sensitive (higher size effect: Cohen's d > 0.5). However, all measures showed excellent intrasession reliability, with strong agreement between the CPM magnitudes. CPM indices were not correlated with TSSP, age or sex, and the psychological scales did not differentiate CPM responders and non-responders.Conclusions: Although the CPM indices showed good reliability, construction of a large database with standardized values for healthy individuals seems necessary for the use of CPM in clinical settings.","PeriodicalId":19959,"journal":{"name":"Pain Management Nursing","volume":" ","pages":""},"PeriodicalIF":1.6000,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pain Management Nursing","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.pmn.2024.12.001","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NURSING","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: Conditioned Pain Modulation (CPM) is a useful tool for testing the functionality of endogenous pain modulation. However, inconsistent results have been obtained in clinical populations, possibly due to the wide variety of CPM protocols used and the influence of demographic and psychological characteristics of the individuals assessed.

Methods: We tested the sensitivity and reliability of four commonly used CPM paradigms in a sample of 58 healthy participants. We also checked how these measures were related to Temporal Summation of Second Pain (TSSP), sociodemographic (age and sex) and psychological variables (anxiety and stress).

Results: CPM results were influenced by the test stimulus used, with tests using pain pressure threshold (PPT) obtaining a greater number of responders (over 65%) and being the most sensitive (higher size effect: Cohen's d > 0.5). However, all measures showed excellent intrasession reliability, with strong agreement between the CPM magnitudes. CPM indices were not correlated with TSSP, age or sex, and the psychological scales did not differentiate CPM responders and non-responders.

Conclusions: Although the CPM indices showed good reliability, construction of a large database with standardized values for healthy individuals seems necessary for the use of CPM in clinical settings.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Pain Management Nursing 医学-护理

CiteScore

3.00

自引率

5.90%

发文量

187

审稿时长

>12 weeks

期刊介绍： This peer-reviewed journal offers a unique focus on the realm of pain management as it applies to nursing. Original and review articles from experts in the field offer key insights in the areas of clinical practice, advocacy, education, administration, and research. Additional features include practice guidelines and pharmacology updates.