[The effects of environmental stressors on cardiovascular health].

Innere Medizin (Heidelberg, Germany) Pub Date : 2025-04-01 Epub Date: 2024-12-30 DOI:10.1007/s00108-024-01823-y
Thomas Münzel, Marin Kuntic, Paul Stamm, Jos Lelieveld, Andreas Daiber
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Abstract

Noncommunicable diseases (NCDs) are responsible for the premature deaths of more than 38 million people each year, making them the leading cause of the global burden of disease, accounting for 70% of global mortality. The majority of these deaths are caused by cardiovascular diseases. The risk of NCDs is closely related to exposure to environmental stressors such as air pollution, noise pollution, artificial light at night, and climate change, including extreme heat, sandstorms, and wildfires. In addition to the traditional risk factors for cardiovascular diseases such as diabetes, high blood pressure, smoking, hypercholesterolemia and genetic predisposition, there is increasing evidence that physicochemical factors in the environment significantly contribute to the high NCD numbers. In addition, urbanization is related to the accumulation and intensification of these stressors. This expert review will summarize the epidemiology and pathophysiology of environmental stressors with a focus on cardiovascular NCDs. In addition, solutions and measures to mitigate the effects of environmental risks, especially concerning cardiovascular diseases, will be discussed.

[环境压力对心血管健康的影响]。
非传染性疾病每年导致3800多万人过早死亡,使其成为全球疾病负担的主要原因,占全球死亡率的70%。这些死亡大多数是由心血管疾病引起的。非传染性疾病的风险与暴露于空气污染、噪音污染、夜间人造光和气候变化(包括极端高温、沙尘暴和野火)等环境压力源密切相关。除了糖尿病、高血压、吸烟、高胆固醇血症和遗传易感性等心血管疾病的传统风险因素外,越来越多的证据表明,环境中的物理化学因素在很大程度上导致了非传染性疾病的高发病率。此外,城市化与这些压力源的积累和加剧有关。本专家综述将以心血管非传染性疾病为重点,总结环境应激源的流行病学和病理生理学。此外,还将讨论减轻环境风险,特别是心血管疾病影响的解决办法和措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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