Efficacy of Conservative Therapy in Juvenile Recurrent Parotitis: A Retrospective Study.

IF 2.9 3区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Oral diseases Pub Date : 2024-12-30 DOI:10.1111/odi.15240

Yanxiang Li, Shutong Niu, Zhiyuan He, Hanyi Zhu, Yimin Liu, Xin Bao, Chuangqi Yu, Huan Shi

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引用次数: 0

Abstract

Objective: The objective of this study is to evaluate the therapeutic effect of conservative treatment in children with juvenile recurrent parotitis (JRP).

Methods: Clinical data from 55 children who were diagnosed with JRP from June 2019 to January 2022 were collected. On admission, patients underwent comprehensive examinations, and a questionnaire was completed by the patients and their parents. Patients received only conservative treatment, including sialagogues, warm compresses, massage and antibiotic treatment.

Results: Episodes after treatment (1.11 ± 1.42) were significantly lower in 55 patients than before treatment (3.35 ± 2.42) (p < 0.001). Clinical symptoms improved for 81.81% and recurred for 60%. Patients who did not respond to treatment were in 3- to 5-year-old group. The serum IgG (p = 0.018), IgA (p = 0.014) and IgM (p = 0.032) levels in the nonresponsive group were significantly higher than those in the improvement group and were either higher than the normal range or at the upper limit. The improvement rate was positively related to the CD8%, and the serum IgA concentration was negatively related to the number of previsit episodes.

Conclusion: Conservative treatment is effective for most children with JRP. Patient responses to treatment may be associated with the maturation of their immune systems. Underlying immune dysregulation should be evaluated, and further treatment is needed in severe cases.

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青少年复发性腮腺炎的保守疗法疗效：回顾性研究

研究目的本研究旨在评估保守治疗对幼年复发性腮腺炎（JRP）患儿的治疗效果：收集2019年6月至2022年1月期间确诊为JRP的55名儿童的临床资料。入院时，患者接受了全面检查，患者及其家长填写了调查问卷。患者仅接受了保守治疗，包括漱口水、热敷、按摩和抗生素治疗：结果：55 名患者治疗后的发病率（1.11 ± 1.42）明显低于治疗前（3.35 ± 2.42）（P 结论：保守治疗对大多数儿童咽喉炎患者有效：保守治疗对大多数JRP患儿有效。患者对治疗的反应可能与其免疫系统的成熟度有关。应评估潜在的免疫失调，严重病例需要进一步治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Oral diseases 医学-牙科与口腔外科

CiteScore

7.60

自引率

5.30%

发文量

325

审稿时长

4-8 weeks

期刊介绍： Oral Diseases is a multidisciplinary and international journal with a focus on head and neck disorders, edited by leaders in the field, Professor Giovanni Lodi (Editor-in-Chief, Milan, Italy), Professor Stefano Petti (Deputy Editor, Rome, Italy) and Associate Professor Gulshan Sunavala-Dossabhoy (Deputy Editor, Shreveport, LA, USA). The journal is pre-eminent in oral medicine. Oral Diseases specifically strives to link often-isolated areas of dentistry and medicine through broad-based scholarship that includes well-designed and controlled clinical research, analytical epidemiology, and the translation of basic science in pre-clinical studies. The journal typically publishes articles relevant to many related medical specialties including especially dermatology, gastroenterology, hematology, immunology, infectious diseases, neuropsychiatry, oncology and otolaryngology. The essential requirement is that all submitted research is hypothesis-driven, with significant positive and negative results both welcomed. Equal publication emphasis is placed on etiology, pathogenesis, diagnosis, prevention and treatment.