Seroprevalence of Helicobacter pylori in a population of 15 to 35 years old in Mashhad.

IF 1.3 Q4 MICROBIOLOGY

Iranian Journal of Microbiology Pub Date : 2024-12-01 DOI:10.18502/ijm.v16i6.17255

Mahdieh Khoshakhlagh, Mohammadreza Tarahomi, Fatemeh Asgharian, Arghavan Kamali, Safoora Sa'd Abadi, Kimia Jafarpour, Samaneh Abolbashari, Mojtaba Meshkat, Aida Gholoobi

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Abstract

Background and objectives: Helicobacter pylori (H. pylori) is a bacterium involved in gastrointestinal disorders with a high prevalence in Iran. We have determined the seroprevalence of H. pylori in the young adult population of Mashhad city for the first time.

Materials and methods: We carried out a cross-sectional study on 933 individuals between the ages of 15 and 35 in Mashhad. The serum level of IgG, IgM, and IgA H. pylori antibodies was determined using enzyme linked immunosorbent assay (ELISA) method.

Results: The average age of the participants including 290 (31.0%) male and 643 (68.9%) female cases was 25.47 ± 5.76. H. pylori IgG was seropositive in 365 (39.1%) of subjects. Occupation (p=0.002), body mass index (p=0.002), marital status (p<0.0001), and age (p<0.007) were meaningfully related to H. pylori IgG seropositivity. Other factors such as sex, educational attainment, history of chronic diseases, and smoking cigarette had no significant relationship with the presence of H. pylori antibodies.

Conclusion: The seroprevalence of H. pylori IgG antibodies in Mashhad's 15 to 35 years old citizens was determined 39.1%. We suggest further studies with larger sample sizes and different age groups as the target population.

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马什哈德15至35岁人群幽门螺杆菌血清患病率

背景和目的：幽门螺杆菌（h.p ylori）是一种与胃肠道疾病有关的细菌，在伊朗发病率很高。我们首次测定了马什哈德市青壮年人群中幽门螺杆菌的血清阳性率。材料和方法：我们在马什哈德对933名年龄在15至35岁之间的个体进行了横断面研究。采用酶联免疫吸附试验（ELISA）检测血清中IgG、IgM、IgA幽门螺杆菌抗体水平。结果：男性290例（31.0%），女性643例（68.9%），平均年龄25.47±5.76岁。幽门螺杆菌IgG血清阳性365例（39.1%）。职业（p=0.002）、体重指数（p=0.002）、婚姻状况（幽门螺杆菌IgG血清阳性）。其他因素如性别、受教育程度、慢性病史和吸烟与幽门螺杆菌抗体的存在无显著关系。结论：马什哈德15 ~ 35岁人群幽门螺杆菌IgG抗体血清阳性率为39.1%。我们建议进一步研究更大的样本量和不同的年龄组作为目标人群。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Microbiology MICROBIOLOGY-

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Microbiology (IJM) is an international, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in the areas of basic and applied research on bacteria and other micro-organisms, including bacteria, viruses, yeasts, fungi, microalgae, and protozoa concerning the development of tools for diagnosis and disease control, epidemiology, antimicrobial agents, clinical microbiology, immunology, Genetics, Genomics and Molecular Biology. Contributions may be in the form of original research papers, review articles, short communications, case reports, technical reports, and letters to the Editor. Research findings must be novel and the original data must be available for review by the Editors, if necessary. Studies that are preliminary, of weak originality or merely descriptive as well as negative results are not appropriate for the journal. Papers considered for publication must be unpublished work (except in an abstract form) that is not under consideration for publication anywhere else, and all co-authors should have agreed to the submission. Manuscripts should be written in English.