Supercharging engineering biology with automation

Sébastien Lambertucci, Faye Deakin
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Abstract

Breakthroughs in engineering biology will solve the challenges facing humanity, by harnessing life itself. Standing in the way of these breakthroughs are the technical challenges of collecting the requisite data. Data variability and reproducibility problems, mean the odds are stacked against emerging biotechs. Automation has long been known to solve both problems; Let a robot do the pipetting and get reproducible data with less hands-on time. Although transitioning to automation has clear benefits, it can introduce additional complexity if done incorrectly. Analytik Jena UK has focused on supporting this transition to automation. We have found the combining of industry expertise with the biology know-how at the bench is paramount. Great automation should empower the scientist. Scientists should be trained on how to harness their automation. Through industry-customer relationships, we have successfully automated platforms for building DNA to antibody development. Through this partnership, we can enable a smooth translation of engineering biology to scalable industrial solutions. In this communication we have highlighted some successful examples where translating engineering biology workflows onto automation has proven beneficial, paving the way to industry ready solutions.

Abstract Image

用自动化为工程生物学增添动力。
工程生物学的突破将通过驾驭生命本身来解决人类面临的挑战。阻碍这些突破的是收集必要数据的技术挑战。数据的可变性和可重复性问题,意味着新兴生物技术的胜算不大。人们早就知道自动化可以解决这两个问题;让机器人来做移液,用更少的动手时间获得可重复的数据。虽然过渡到自动化有明显的好处,但如果操作不当,它可能会引入额外的复杂性。Analytik Jena UK专注于支持这种向自动化的过渡。我们发现,将行业专业知识与生物学专业知识相结合是至关重要的。伟大的自动化应该赋予科学家权力。科学家应该接受培训,学习如何利用他们的自动化技术。通过行业-客户关系,我们已经成功地自动化了构建DNA到抗体开发的平台。通过这种伙伴关系,我们可以将工程生物学顺利转化为可扩展的工业解决方案。在本次交流中,我们强调了一些成功的例子,将工程生物学工作流程转化为自动化已被证明是有益的,为行业准备好的解决方案铺平了道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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