Yi Wang, Xianchao Zhao, Jiafeng Ren, Shengwen Xue, Yuhang Liu, Liping Zhang, Mengmeng Fan, Changjun Su, Jin-Xiang Cheng
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引用次数: 0
Abstract
Purpose: Light is a crucial factor influencing sleep arousal patterns. This meta-analysis investigates the efficacy of light therapy (LT) for insomnia treatment.
Methods: Five electronic databases were independently searched by two reviewers until August 2024. The literature screening focused specifically on populations with insomnia complaints treated by LT. Weighted Mean Difference (WMD) and 95% Confidence Interval (CI) were used as statistical tools, while the Cochrane Risk of Bias tool version 2 (RoB 2) was employed to assess the quality of evidence. A total of 10 randomized controlled trials (RCTs) were analyzed.
Results: The results demonstrated that LT showed statistically significant improvements in subjective sleep quality, as evidenced by a reduction in Pittsburgh sleep quality scale (PSQI) scores by -2.89 (95% CI = -4.80 to -0.97) and Insomnia severity index (ISI) scores by -2.16 (95% CI = -4.23 to -0.08) post-intervention. Additionally, actigraphy revealed a statistically significant increase in total sleep time (TST) by 16.78 min (95% CI = 0.67 to 32.89) and a decrease in wake after sleep onset (WASO) by -12.91 min (95% CI = -25.62 to -0.20) by LT.
Conclusion: The preliminary results of the study suggest that LT has some efficacy in improving sleep quality in insomnia. However, it needs to be validated in future clinical trials with larger samples.
目的：光是影响睡眠唤醒模式的关键因素。本荟萃分析调查了光疗法（LT）治疗失眠的疗效。方法：由2位审稿人独立检索5个电子数据库，截止到2024年8月。文献筛选专门针对接受lt治疗的失眠主诉人群。采用加权平均差（WMD）和95%置信区间（CI）作为统计工具，采用Cochrane风险偏倚工具第2版（RoB 2）评估证据质量。共分析10项随机对照试验（rct）。结果：结果表明，LT在主观睡眠质量方面有统计学意义的改善，干预后匹兹堡睡眠质量量表（PSQI）得分降低-2.89 (95% CI = -4.80至-0.97)，失眠严重指数（ISI）得分降低-2.16 （95% CI = -4.23至-0.08）。此外，活动图显示，LT可使总睡眠时间（TST）增加16.78 min (95% CI = 0.67 ~ 32.89)，使醒后睡眠时间（WASO）减少-12.91 min （95% CI = -25.62 ~ -0.20）。结论：本研究初步结果提示LT对改善失眠症患者的睡眠质量有一定疗效。然而，它需要在未来更大样本的临床试验中得到验证。
期刊介绍：
The journal Sleep and Breathing aims to reflect the state of the art in the international science and practice of sleep medicine. The journal is based on the recognition that management of sleep disorders requires a multi-disciplinary approach and diverse perspectives. The initial focus of Sleep and Breathing is on timely and original studies that collect, intervene, or otherwise inform all clinicians and scientists in medicine, dentistry and oral surgery, otolaryngology, and epidemiology on the management of the upper airway during sleep.
Furthermore, Sleep and Breathing endeavors to bring readers cutting edge information about all evolving aspects of common sleep disorders or disruptions, such as insomnia and shift work. The journal includes not only patient studies, but also studies that emphasize the principles of physiology and pathophysiology or illustrate potentially novel approaches to diagnosis and treatment. In addition, the journal features articles that describe patient-oriented and cost-benefit health outcomes research. Thus, with peer review by an international Editorial Board and prompt English-language publication, Sleep and Breathing provides rapid dissemination of clinical and clinically related scientific information. But it also does more: it is dedicated to making the most important developments in sleep disordered breathing easily accessible to clinicians who are treating sleep apnea by presenting well-chosen, well-written, and highly organized information that is useful for patient care.
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