Addressing the Effect of Exercise on Glial Cells: Focus on Ependymal Cells.

IF 2.5 4区 医学 Q3 NEUROSCIENCES
Grazia Maugeri, Alessandra Amato, Giuseppe Evola, Velia D'Agata, Giuseppe Musumeci
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引用次数: 0

Abstract

A growing body of research highlights the positive impact of regular physical activity on improving physical and mental health. On the other hand, physical inactivity is one of the leading risk factors for noncommunicable diseases and death worldwide. Exercise profoundly impacts various body districts, including the central nervous system. Here, overwhelming evidence exists that physical exercise affects neurons and glial cells, by promoting their interaction. Physical exercise directly acts on ependymal cells by promoting their proliferation and activation, maintaing brain homeostasis in healthy animals and promote locomotor recovery after spinal cord injury. This review aims to describe the main anatomical characteristics and functions of ependymal cells and provide an overview of the effects of different types of physical exercise on glial cells, focusing on the ependymal cells.

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来源期刊
CiteScore
2.80
自引率
5.60%
发文量
173
审稿时长
2 months
期刊介绍: JIN is an international peer-reviewed, open access journal. JIN publishes leading-edge research at the interface of theoretical and experimental neuroscience, focusing across hierarchical levels of brain organization to better understand how diverse functions are integrated. We encourage submissions from scientists of all specialties that relate to brain functioning.
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