Active surveillance of hospital-acquired infections in Pediatric Intensive Care Unit: a single center study.

IF 0.5 4区医学 Q4 MICROBIOLOGY

Epidemiologie Mikrobiologie Imunologie Pub Date : 2024-01-01 DOI:10.61568/emi/11-6390/20241024/138874

M Fulová, M Kotrbancová, J Perželová, A Bražinová

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引用次数: 0

Abstract

Objective: The aim of our study was to describe and analyze HAI incidence, etiology and risk factors in pediatric intensive care unit (ICU).

Background: Intensive care patients are at high risk of hospital-acquired infections (HAI) due to their underlying diseases and exposure to invasive devices.

Methods: The study group consisted of patients admitted to children's hospital ICU for more than 2 days during a six-month period (267 patients, 1570 patient-days). We used the European Centre for Disease Prevention and Control standard protocol HAI-Net ICU v2.2 for data collection.

Results: HAI occurred in 17 (6.4%) included patients (10.8 infections per 1000 patient-days). The most frequent were catheter-related bloodstream infections (33%, 7.6 per 1000 catheter-days) and intubation-associated pneumonia (25%, 10.9 per 1000 intubation-days). Gram-negative bacteria (Pseudomonas aeruginosa, Klebsiella spp.) were identified as the most common etiological agents. Significantly higher risk of HAI had patients with central venous catheter (OR: 14.5, 95% CI 3.2-65.1), intubated (OR: 14.4, 95% CI 4.4-46.2), with Pediatric Index of Mortality score higher than 10 (OR: 17, 95% CI 2.7-111.5) and with previous bacterial or/ and fungal colonization (OR: 30.6, 95% CI 9.2-101.3).

Conclusions: Active surveillance identified unreported HAI cases and proved to be an effective tool of infection control.

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儿科重症监护病房医院获得性感染的主动监测：一项单中心研究

目的：本研究的目的是描述和分析儿科重症监护病房（ICU） HAI的发病率、病因和危险因素。背景：重症监护患者由于其潜在疾病和暴露于侵入性器械，是医院获得性感染（HAI）的高危人群。方法：研究组为6个月期间在儿童医院ICU住院2天以上的患者（267例，1570患者日）。我们使用欧洲疾病预防和控制中心标准协议HAI-Net ICU v2.2进行数据收集。结果：17例（6.4%）患者发生HAI（10.8例/ 1000患者日）。最常见的是导管相关血流感染（33%，每1000导管日7.6例）和插管相关肺炎（25%，每1000插管日10.9例）。革兰氏阴性菌（铜绿假单胞菌、克雷伯氏菌）是最常见的病原。中心静脉置管（OR: 14.5, 95% CI 3.2-65.1）、插管（OR: 14.4, 95% CI 4.4-46.2）、儿科死亡率指数评分高于10 （OR: 17, 95% CI 2.7-111.5）、既往有细菌或/和真菌定植（OR: 30.6, 95% CI 9.2-101.3）的患者发生HAI的风险明显较高。结论：主动监测发现了未报告的HAI病例，并被证明是感染控制的有效工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Epidemiologie Mikrobiologie Imunologie Medicine-Immunology and Allergy

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The journal publishes original papers, information from practice, reviews on epidemiological and microbiological subjects. Sufficient space is devoted to diagnostic methods from medical microbiology, parasitology, immunology, and to general aspects and discussions pertaining to preventive medicine. It also brings translations and book reviews useful for medical doctors and research workers and professionals in public health.