[Potential of ultrasonography in determination of orbital inflammation activity in granulomatosis with polyangiitis].

Q3 Medicine

Vestnik oftalmologii Pub Date : 2024-01-01 DOI:10.17116/oftalma202414006132

D S Ismailova, O V Eksarenko, P I Novikov

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引用次数: 0

Abstract

Purpose: This study investigates the capabilities of ultrasonography (US) in determing the stage of orbital inflammation in patients with granulomatosis with polyangiitis (GPA).

Material and methods: The study included 24 patients (8 men and 16 women) with diffuse orbital tissue involvement in GPA. Group 1 (active stage) included nine patients, while group 2 (inactive stage) consisted of 18 patients. Three patients were in both groups. In four patients (16.7%), the inflammation was bilateral, while the remaining 20 (83.3%) had unilateral orbital involvement. A total of 13 US examinations were conducted in group 1, and 22 in group 2. All patients underwent orbital US, including duplex scanning of ocular and orbital vessels, along with multiplanar combined spatial analysis of the orbital inflammatory mass.

Results: The ultrasound characteristics in orbital GPA, specifically acoustic density, presence of pathological blood flow within and around the inflammatory mass, and flow intensity varied according to the stage of the inflammatory process.

Conclusion: Ultrasound is a non-invasive and accessible method for assessing inflammation activity in orbital GPA.

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[超声检查在肉芽肿合并多血管炎患者眼眶炎症活动性的潜力]。

目的：探讨超声（US）对肉芽肿合并多血管炎（GPA）患者眼眶炎症分期的诊断价值。材料和方法：本研究纳入24例GPA弥漫性眼眶组织受累患者（8男16女）。组1（活动期）9例，组2（非活动期）18例。两组均有3例患者。其中4例（16.7%）为双侧炎症，其余20例（83.3%）为单侧眼眶受累。1组共13例，2组22例。所有患者均行眼眶US，包括眼血管和眼眶血管的双工扫描，以及眼眶炎性肿块的多平面联合空间分析。结果：眼眶GPA的超声特征，特别是声密度、炎性肿块内部和周围是否存在病理性血流以及血流强度随炎症过程的阶段而变化。结论：超声是一种无创、简便的评价眼眶GPA炎症活动性的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vestnik oftalmologii Medicine-Ophthalmology

CiteScore

0.80

自引率

0.00%

发文量

129

期刊介绍： The journal publishes materials on the diagnosis and treatment of eye diseases, hygiene of vision, prevention of ophthalmic affections, history of Russian ophthalmology, organization of ophthalmological aid to the population, as well as the problems of special equipment. Original scientific articles and surveys on urgent problems of theory and practice of Russian and foreign ophthalmology are published. The journal contains book reviews on ophthalmology, information on the activities of ophthalmologists" scientific societies, chronicle of congresses and conferences.The journal is intended for ophthalmologists and scientific workers dealing with clinical problems of diseases of the eye and physiology of vision.