[Research progress in biological activities and oocyte aging-regulating effect of EGCG].

Q4 Biochemistry, Genetics and Molecular Biology

Sheng wu gong cheng xue bao = Chinese journal of biotechnology Pub Date : 2024-12-25 DOI:10.13345/j.cjb.240192

Weiying Zhang, Huizhu Zhang, Yujun Li, Daoliang Lan, Xianrong Xiong, Yaying Wang, Jian Li, Honghong He

引用次数: 0

Abstract

Epigallocatechin gallate (EGCG), the predominant polyphenol in green tea, exerts a spectrum of physiological activities, including antioxidant, anticancer, and anti-inflammatory effects. Emerging research underscores the significance of EGCG in modulating oocyte aging. EGCG can enhance antioxidant defenses, improve mitochondrial functions, and inhibit apoptotic pathways, thereby retarding the aging of oocytes. This review delineates the main molecular features of EGCG and expounds its regulatory mechanisms concerning oocyte aging, enriching the knowledge on the role of EGCG in the amelioration of oocyte aging.

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EGCG生物活性及调节卵母细胞衰老作用的研究进展

表没食子儿茶素没食子酸酯（EGCG）是绿茶中主要的多酚，具有一系列的生理活性，包括抗氧化、抗癌和抗炎作用。新兴研究强调了EGCG在调节卵母细胞衰老中的重要性。EGCG可以增强抗氧化防御，改善线粒体功能，抑制凋亡通路，从而延缓卵母细胞的衰老。本文综述了EGCG的主要分子特征，阐述了EGCG对卵母细胞衰老的调控机制，丰富了EGCG在改善卵母细胞衰老中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sheng wu gong cheng xue bao = Chinese journal of biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology

CiteScore

1.50

自引率

0.00%

发文量

298

期刊介绍： Chinese Journal of Biotechnology (Chinese edition) , sponsored by the Institute of Microbiology, Chinese Academy of Sciences and the Chinese Society for Microbiology, is a peer-reviewed international journal. The journal is cited by many scientific databases , such as Chemical Abstract (CA), Biology Abstract (BA), MEDLINE, Russian Digest , Chinese Scientific Citation Index (CSCI), Chinese Journal Citation Report (CJCR), and Chinese Academic Journal (CD version). The Journal publishes new discoveries, techniques and developments in genetic engineering, cell engineering, enzyme engineering, biochemical engineering, tissue engineering, bioinformatics, biochips and other fields of biotechnology.