Acute effect of exercise on appetite-related factors in males with obesity: A pilot study.

IF 2.2 Q3 PHYSIOLOGY

Physiological Reports Pub Date : 2024-12-01 DOI:10.14814/phy2.70167

Sogand Asri, Farhad Rahmani-Nia, Payam Saidie, Timothy J Fairchild, Shahin Khodabandeh

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引用次数: 0

Abstract

To investigate the role of appetite-related factors, including interleukin 6 (IL-6), irisin, interleukin 7 (IL-7), neuropeptide Y (NPY), and leptin, on appetite perception in males with obesity. Eleven males (BMI 35.3 ± 4.2 kg/m², V̇O_2peak 29 ± 3.1 mL/kg/min) participated in two experimental trials (MICE: 60 min of cycling at 60% of V̇O_2peak; CTRL: 60 min of quiet resting) using a crossover design. Appetite parameters, including IL-6, IL-7, irisin, and leptin, were measured. Additionally, appetite perception was assessed. IL-6 concentration increased significantly immediately post-exercise (95% CI: [2.207-12.192] pg/mL, p = 0.007) and remained elevated 1 hour post-exercise (95% CI: [2.326-11.855] pg/mL, p = 0.006) compared to CTRL. Irisin also rose significantly immediately post-exercise (95% CI: [0.084-3.061] ng/mL, p = 0.039). NPY decreased significantly 1 h post-exercise (95% CI: [(-20.601) - (-1.380)] ng/L, p = 0.027). No significant differences were observed for IL-7 (p = 0.748, $η_{p}^{2}$ = 0.077) and leptin (p = 0.285, $η_{p}^{2} = 0.061$ ). Appetite perceptions were suppressed immediately post-exercise (95% CI: [3.407-19.547] mm, p = 0.008) compared to CTRL. Sixty minutes of MICE increased IL-6 and irisin concentrations while suppressed NPY and appetite perceptions in males with obesity.

查看原文本刊更多论文

运动对肥胖男性食欲相关因素的急性影响：一项初步研究。

探讨白介素6 （IL-6）、鸢尾素、白介素7 （IL-7）、神经肽Y （NPY）和瘦素等食欲相关因子在肥胖男性食欲感知中的作用。11名男性（BMI 35.3±4.2 kg/m2， V / o2峰值29±3.1 mL/kg/min）参加了两项实验（小鼠：60点骑车60 min）% of V̇O2peak; CTRL: 60 min of quiet resting) using a crossover design. Appetite parameters, including IL-6, IL-7, irisin, and leptin, were measured. Additionally, appetite perception was assessed. IL-6 concentration increased significantly immediately post-exercise (95% CI: [2.207-12.192] pg/mL, p = 0.007) and remained elevated 1 hour post-exercise (95% CI: [2.326-11.855] pg/mL, p = 0.006) compared to CTRL. Irisin also rose significantly immediately post-exercise (95% CI: [0.084-3.061] ng/mL, p = 0.039). NPY decreased significantly 1 h post-exercise (95% CI: [(-20.601) - (-1.380)] ng/L, p = 0.027). No significant differences were observed for IL-7 (p = 0.748, η p 2 $$ {\eta}_p^2 $$ = 0.077) and leptin (p = 0.285, η p 2 = 0.061 $$ {\eta}_p^2=0.061 $$ ). Appetite perceptions were suppressed immediately post-exercise (95% CI: [3.407-19.547] mm, p = 0.008) compared to CTRL. Sixty minutes of MICE increased IL-6 and irisin concentrations while suppressed NPY and appetite perceptions in males with obesity.

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来源期刊

Physiological Reports PHYSIOLOGY-

CiteScore

4.20

自引率

4.00%

发文量

374

审稿时长

9 weeks

期刊介绍： Physiological Reports is an online only, open access journal that will publish peer reviewed research across all areas of basic, translational, and clinical physiology and allied disciplines. Physiological Reports is a collaboration between The Physiological Society and the American Physiological Society, and is therefore in a unique position to serve the international physiology community through quick time to publication while upholding a quality standard of sound research that constitutes a useful contribution to the field.