Impact of the relationship between renal pedicles and tumors on surgical outcomes for non-high-risk abdominal neuroblastoma.

Abstract

Purpose: To assess the impact of the relationship between renal pedicles and tumors on surgical outcomes in patients with non-high-risk abdominal neuroblastoma.

Methods: We retrospectively analyzed cases of neuroblastoma without metastasis treated at our hospital between March 2002 and December 2023. Cases in which surgical resection was performed were divided into three groups according to imaging findings at the time of diagnosis and before surgery: Group E (tumor encasing renal pedicles), Group C (tumor in contact with renal pedicles), and Group S (tumor separated from renal pedicles).

Results: Among 256 neuroblastoma cases diagnosed during the study period, 27 non-high-risk cases that underwent surgery for partial abdominal tumor resection or greater were included. The numbers of cases in the S group, C group, and E group, respectively, were 7, 9, and 11 at diagnosis, and 8, 14, and 5 before surgery. Renal complications (combined concurrent renal resection and post-operative renal atrophy) were seen in five E group cases at the time of diagnosis, and two C group cases and three E group cases preoperatively.

Conclusion: In non-high-risk abdominal neuroblastomas, tumors encased in the renal pedicles have the highest risk of renal complications, followed by tumors in contact with the renal pedicles.