{"title":"High-resolution vessel wall MRI in Moyamoya disease: a systematic review and meta-analysis of diagnostic and prognostic applications.","authors":"Maryam Shahabi, Negar Zareshahi, Iman Kiani, Mahdi Gouravani, Alireza Beikmarzehei, Yalda Farahmand, Ehsan Ranjbar, Armin Tafazolimoghadam, Mohammadamin Parsaei, Hossein Sanjari Moghaddam, Alejandro M Spiotta","doi":"10.1007/s00234-024-03515-8","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the narrowing of arteries at the brain's base. While cerebral angiography is the gold standard for diagnosis, high-resolution vessel wall magnetic resonance imaging (VW-MRI) has recently emerged as a non-invasive diagnostic tool. This systematic review aims to provide insights into the role of VW-MRI in enhancing the diagnosis and management of MMD.</p><p><strong>Method: </strong>A systematic search was conducted in PubMed, Embase, Scopus, and Web of Science for relevant articles on December 5, 2023. Demographic data, the outer diameter of the vessel, vessel wall contrast enhancement (VW-CE) and its pattern, vessel wall thickening and its pattern, remodeling index, and vessel area were extracted. In the analysis proportions were pooled using a random-effects model with logit transformation where applicable. Quality assessment was conducted using the Newcastle-Ottawa scale.</p><p><strong>Result: </strong>Of the 6035 identified studies in the primary search, 19 met the inclusion criteria. Among the reviewed studies, the most commonly reported variations in patients with MMD using VW-MRI was VW-CE (84.21%) and its pattern (52.63%). The pooled prevalence of enhanced lesions in MMD was 0.55 (95% CI: 0.29-0.79), with ratio of concentric lesions being 0.98 (95% CI: 0.72-1.00, I²: 37%). The remodeling index across three studies showed a pooled estimate of 0.41 (95% CI: 0.11-0.72, I²: 99%).</p><p><strong>Discussion: </strong>VW-MRI emerges as a promising non-invasive tool for enhancing diagnosis of MMD, potentially aiding in disease differentiation and predicting complications. However, standardization and further research are essential to solidify VW-MRI's role.</p>","PeriodicalId":19422,"journal":{"name":"Neuroradiology","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroradiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00234-024-03515-8","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by the narrowing of arteries at the brain's base. While cerebral angiography is the gold standard for diagnosis, high-resolution vessel wall magnetic resonance imaging (VW-MRI) has recently emerged as a non-invasive diagnostic tool. This systematic review aims to provide insights into the role of VW-MRI in enhancing the diagnosis and management of MMD.
Method: A systematic search was conducted in PubMed, Embase, Scopus, and Web of Science for relevant articles on December 5, 2023. Demographic data, the outer diameter of the vessel, vessel wall contrast enhancement (VW-CE) and its pattern, vessel wall thickening and its pattern, remodeling index, and vessel area were extracted. In the analysis proportions were pooled using a random-effects model with logit transformation where applicable. Quality assessment was conducted using the Newcastle-Ottawa scale.
Result: Of the 6035 identified studies in the primary search, 19 met the inclusion criteria. Among the reviewed studies, the most commonly reported variations in patients with MMD using VW-MRI was VW-CE (84.21%) and its pattern (52.63%). The pooled prevalence of enhanced lesions in MMD was 0.55 (95% CI: 0.29-0.79), with ratio of concentric lesions being 0.98 (95% CI: 0.72-1.00, I²: 37%). The remodeling index across three studies showed a pooled estimate of 0.41 (95% CI: 0.11-0.72, I²: 99%).
Discussion: VW-MRI emerges as a promising non-invasive tool for enhancing diagnosis of MMD, potentially aiding in disease differentiation and predicting complications. However, standardization and further research are essential to solidify VW-MRI's role.
期刊介绍：
Neuroradiology aims to provide state-of-the-art medical and scientific information in the fields of Neuroradiology, Neurosciences, Neurology, Psychiatry, Neurosurgery, and related medical specialities. Neuroradiology as the official Journal of the European Society of Neuroradiology receives submissions from all parts of the world and publishes peer-reviewed original research, comprehensive reviews, educational papers, opinion papers, and short reports on exceptional clinical observations and new technical developments in the field of Neuroimaging and Neurointervention. The journal has subsections for Diagnostic and Interventional Neuroradiology, Advanced Neuroimaging, Paediatric Neuroradiology, Head-Neck-ENT Radiology, Spine Neuroradiology, and for submissions from Japan. Neuroradiology aims to provide new knowledge about and insights into the function and pathology of the human nervous system that may help to better diagnose and treat nervous system diseases. Neuroradiology is a member of the Committee on Publication Ethics (COPE) and follows the COPE core practices. Neuroradiology prefers articles that are free of bias, self-critical regarding limitations, transparent and clear in describing study participants, methods, and statistics, and short in presenting results. Before peer-review all submissions are automatically checked by iThenticate to assess for potential overlap in prior publication.
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