Revisiting the concept of giant viruses.

IF 2.6 4区医学 Q3 IMMUNOLOGY

Microbes and Infection Pub Date : 2024-12-24 DOI:10.1016/j.micinf.2024.105467

Jônatas Santos Abrahão

引用次数: 0

Abstract

Giant viruses have fascinated the scientific community due to their immense particles and extensive genomes. A significant surge of interest in the field has been observed over the past 20 years following the discovery of mimiviruses, the first amoeba-infecting viruses described. However, with the discovery of new amoeba viruses and those from other protists, the concept of "giant viruses" has become increasingly controversial in the scientific literature. This commentary revisits the historical and conceptual foundations of the term "giant virus" and explores its implications for virology.

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重新审视巨型病毒的概念。

巨型病毒因其巨大的颗粒和广泛的基因组而吸引了科学界。在发现mimivirus（第一种被描述的感染变形虫的病毒）之后，在过去的20年里，人们对这一领域的兴趣激增。然而，随着新的变形虫病毒和其他原生生物病毒的发现，“巨型病毒”的概念在科学文献中变得越来越有争议。本评论回顾了“巨型病毒”一词的历史和概念基础，并探讨了其对病毒学的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Microbes and Infection 医学-病毒学

CiteScore

12.60

自引率

1.70%

发文量

审稿时长

40 days

期刊介绍： Microbes and Infection publishes 10 peer-reviewed issues per year in all fields of infection and immunity, covering the different levels of host-microbe interactions, and in particular: the molecular biology and cell biology of the crosstalk between hosts (human and model organisms) and microbes (viruses, bacteria, parasites and fungi), including molecular virulence and evasion mechanisms. the immune response to infection, including pathogenesis and host susceptibility. emerging human infectious diseases. systems immunology. molecular epidemiology/genetics of host pathogen interactions. microbiota and host "interactions". vaccine development, including novel strategies and adjuvants. Clinical studies, accounts of clinical trials and biomarker studies in infectious diseases are within the scope of the journal. Microbes and Infection publishes articles on human pathogens or pathogens of model systems. However, articles on other microbes can be published if they contribute to our understanding of basic mechanisms of host-pathogen interactions. Purely descriptive and preliminary studies are discouraged.