Ruptured Ovarian Mature Cystic Teratoma with Adenocarcinoma Transformation: A Case Report.

IF 2.5 4区医学 Q2 OBSTETRICS & GYNECOLOGY

International Journal of Women's Health Pub Date : 2024-12-21 eCollection Date: 2024-01-01 DOI:10.2147/IJWH.S490109

Liping Xu, Jinxiao Jiang, Qingxia Geng, Yinmin Zhang

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引用次数: 0

Abstract

Purpose: Ovarian mature cystic teratoma (MCT) is the most common ovarian tumor, and only a small fraction undergoes malignant transformation. The most prevalent malignant type of the ovary is squamous cell carcinoma, followed by adenocarcinoma. However, ruptured ovarian mature cystic teratoma with adenocarcinoma transformation is extremely rare.

Case presentation: A 75-year-old postmenopausal woman presented to the emergency room with abdominal pain following a CT examination, the patient was diagnosed with a ruptured ovarian MCT. Subsequently, surgery was performed. Finally, she was diagnosed with adenocarcinoma tumor originating from the MCT of the ovary based on histopathology and immunohistochemistry examination. Following six cycles of chemotherapy with carboplatin and paclitaxel, the patient underwent long-term follow-up, during which no recurrence was observed over 10 months of examinations.

Conclusion: The cases of ruptured cystic teratomas are rare, and ruptured cancerous transformation in MCT is infrequently documented in the literature. Therefore, special attention should be paid when encountering such cases in medical practice, as they can easily be misdiagnosed as benign ovarian tumors.

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卵巢破裂性成熟囊性畸胎瘤伴腺癌转化1例。

目的：卵巢成熟囊性畸胎瘤（MCT）是最常见的卵巢肿瘤，仅一小部分发生恶性转化。卵巢最常见的恶性类型是鳞状细胞癌，其次是腺癌。然而，卵巢破裂成熟囊性畸胎瘤伴腺癌转化是极为罕见的。病例介绍：一名75岁绝经后妇女在CT检查后因腹痛来到急诊室，患者被诊断为卵巢MCT破裂。随后进行手术治疗。经组织病理及免疫组化检查，诊断为卵巢MCT腺癌。在卡铂和紫杉醇化疗6个周期后，患者进行了长期随访，在10个月的检查中未观察到复发。结论：囊性畸胎瘤的破裂是罕见的，而MCT的癌性转化的破裂在文献中是罕见的。因此，在医疗实践中遇到此类病例时应特别注意，因为它们很容易被误诊为卵巢良性肿瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Women's Health OBSTETRICS & GYNECOLOGY-

CiteScore

3.70

自引率

0.00%

发文量

194

审稿时长

16 weeks

期刊介绍： International Journal of Women''s Health is an international, peer-reviewed, open access, online journal. Publishing original research, reports, editorials, reviews and commentaries on all aspects of women''s healthcare including gynecology, obstetrics, and breast cancer. Subject areas include: Chronic conditions including cancers of various organs specific and not specific to women Migraine, headaches, arthritis, osteoporosis Endocrine and autoimmune syndromes - asthma, multiple sclerosis, lupus, diabetes Sexual and reproductive health including fertility patterns and emerging technologies to address infertility Infectious disease with chronic sequelae including HIV/AIDS, HPV, PID, and other STDs Psychological and psychosocial conditions - depression across the life span, substance abuse, domestic violence Health maintenance among aging females - factors affecting the quality of life including physical, social and mental issues Avenues for health promotion and disease prevention across the life span Male vs female incidence comparisons for conditions that affect both genders.