One-year outcomes of selective laser trabeculoplasty for open-angle glaucoma in Indian eyes.

IF 2.1 4区 医学 Q2 OPHTHALMOLOGY
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-12-27 DOI:10.4103/IJO.IJO_1434_24
Anuj Sharma, Arpita Nayak, Shamika Ghaisas, K Vidya
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引用次数: 0

Abstract

Purpose: To assess the effectiveness of selective laser trabeculoplasty (SLT) in Indian eyes with open-angle glaucoma (OAG).

Settings and design: Single-center, prospective, interventional study.

Methods: Patients undergoing SLT from January 2014 to June 2018 for OAG were included in the study. Treatment-naive naive as well as patients on antiglaucoma medications (AGM) with suboptimal intraocular pressure (IOP) control were included. The main outcome measure was the percentage reduction in IOP. Complete success was defined as IOP reduction > 20% from baseline after 12 months or reduction in the number of AGM. Qualified success was defined as > 20% IOP reduction at 12 months with AGM. Secondary outcomes were occurrence of adverse events and factors predicting treatment outcomes.

Results: A total of 104 eyes of 62 Indian patients underwent SLT for OAG. Eighty-three (79.81%) eyes were treatment-naïve, and 21 (20.19%) eyes were on AGM. The median (IQR) baseline IOP was 20 (16-26) mmHg. At 12 months, the median IOP was 16 (4-19) mmHg, the median decrease in IOP was 4 (0-6.5) mmHg, and the percentage reduction in IOP was 17.42% (0%-30.76%). Maximum IOP reduction was noted at 12 months. Overall, success was achieved in 48 (46.15%) patients. Five eyes (4.8%) experienced minor SLT-related complications. Age, gender, prior use of AGM, type of OAG, and higher baseline IOP were not found to be predictive factors for treatment outcome.

Conclusion: SLT was found to be a relatively safe and effective procedure in Indian eyes with OAG.

选择性激光小梁成形术治疗开角型青光眼的一年疗效。
目的:评价选择性激光小梁成形术(SLT)治疗开角型青光眼的疗效。背景和设计:单中心、前瞻性、干预性研究。方法:纳入2014年1月至2018年6月因OAG接受SLT治疗的患者。未接受治疗的患者以及服用抗青光眼药物(AGM)且眼压(IOP)控制不佳的患者被纳入研究。主要结局指标是IOP降低的百分比。完全成功的定义是12个月后IOP较基线降低20%或AGM数量减少。合格的成功定义为在AGM 12个月时IOP降低20%。次要结局是不良事件的发生和预测治疗结果的因素。结果:62例印度患者共104眼行SLT治疗OAG。83只(79.81%)眼为treatment-naïve, 21只(20.19%)眼为AGM。中位(IQR)基线IOP为20 (16-26)mmHg。12个月时,中位IOP为16 (4-19)mmHg,中位IOP下降为4 (0-6.5)mmHg, IOP下降百分比为17.42%(0%-30.76%)。在12个月时观察到最大的IOP下降。总体而言,48例(46.15%)患者获得成功。5只眼(4.8%)出现轻度slt相关并发症。年龄、性别、既往使用AGM、OAG类型和较高的基线IOP不是治疗结果的预测因素。结论:SLT是治疗印度眼OAG的一种相对安全有效的手术方法。
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来源期刊
CiteScore
3.80
自引率
19.40%
发文量
1963
审稿时长
38 weeks
期刊介绍: Indian Journal of Ophthalmology covers clinical, experimental, basic science research and translational research studies related to medical, ethical and social issues in field of ophthalmology and vision science. Articles with clinical interest and implications will be given preference.
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