Nick Drake: A Troubled Mind, a Troublesome ‘Cure’

IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY
David S. Baldwin
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There was much to ponder, whilst travelling home from the University of Birmingham: and my dream-like musings continued that same evening, when the BBC Radio 3 Promenade (‘Prom’) concert broadcast was devoted solely to ‘An Orchestral Celebration’ of the music of Nick Drake, who died when aged only twenty-six, almost fifty years before, in November 1974.</p><p>Born in Rangoon, Burma (now Yangon, Myanmar), to expatriate Britons—his father worked as a Civil Engineer, his mother came from a senior Indian Civil Service family—Nicholas Rodney Drake moved with his family to the UK as a toddler, went to a preparatory boarding school, then boarded at Marlborough College, before somewhat unexpectedly scraping into Fitzwilliam College Cambridge in 1967, to read English Literature. But he left Cambridge two years later, nine months before graduation, against the advice of his tutors and family, to further his musical career: his first album, the wistful and pastoral <i>Five Leaves Left</i> had been released a few months earlier. A strike-delayed second album, <i>Bryter Later</i>, sometimes considered to be ensemble-heavy, appeared in March 1971. Both were critically acclaimed by music journalists and other musicians, but neither gained much traction with the buying public. His third album, the desolate and intermittently agitated <i>Pink Moon</i>, was released in February 1972, but probably sold less than its predecessors.</p><p>Characteristically reticent and often seeming aloof, he became steadily more isolated and withdrawn, possibly linked to or worsened by regular smoking of cannabis, which he started before University. He declared himself increasingly reluctant to play the live concerts which could probably have led to wider recognition and greater sales. Although he was an astonishingly adept, technically innovative guitarist and widely respected lyricist, it was more challenging for him to synchronise playing with singing. He sought company but was uncommunicative whilst in it. He neglected himself, seemed erratic and unpredictable, and sometimes had observable difficulty in sequencing tasks, such as making tea. Increasing parental concern prompted admission to the local inpatient psychiatric unit, where after a few weeks the thoughtful, compassionate consultant psychiatrist suggested their 23-year old son might suffer from simple-type schizophrenia.</p><p>Psychiatric diagnoses can be unreliable, and treatment plans are often contested. Drake himself stated that taking medication was ‘against my principles’. The well-meaning social worker attached to the local unit indicated that psychotropic medication was not as beneficial as psychotherapy, and recommended referral to a Laingian psychotherapist. By contrast, a regional specialist consultant psychiatrist recommended electroconvulsive therapy (ECT). Subsequently, an eminent London teaching hospital consultant, seeing Drake on a private basis, preferred the diagnosis of depressive illness and recommended combination treatment with amitriptyline, trifluoperazine, orphenadrine and diazepam. Drake did not attend an offered appointment with the Laing-founded Philadelphia Association. ECT was administered just once. Periods of medication adherence were accompanied by some beneficial effects, including the desire to write new material, but treatments and improvements were not sustained. He became increasingly despondent, took a large intentional overdose of diazepam (thirty-six tablets) in February 1973, and died in autumn of the following year after a substantial overdose (approximately sixty tablets) of amitriptyline: the coroner's inquest recorded a verdict of suicide ‘when suffering from a depressive illness’.</p><p>On balance, the multiple insightful observations of friends and peers featured within the forensically-detailed biography (Jack <span>2023</span>) align with some important features (including negative symptoms and disorganisation) indicating a probable diagnosis of schizophrenia. His father believed this to be the case and had joined the National Schizophrenia Fellowship for support and advice: the always supportive, loving family were troubled by a sense of bewildered helplessness. They had not been made aware that amitriptyline could be fatal when taken in even small overdoses. A close friend from his University days, who subsequently became a psychiatrist, felt that regardless of diagnosis, psychotropic medication alone would have been insufficient to result in much improvement.</p><p>But regardless of favoured diagnosis, the inpatient and outpatient clinical care which Drake received was unable to arrest an inexorable decline. Current mental health services—such as early intervention in psychosis teams—would strive to provide a case-managed, community-based, multi-disciplinary approach including assertive outreach, advice against returning to cannabis smoking, psychotropic medication optimisation (perhaps involving long-acting injectable antipsychotic treatment), psychological treatment, recovery-based activities and family involvement and support. With such provisions at the time, the outcome for this troubled young man may well have been different.</p><p>An awareness of his struggle with personal mental health problems seems important when considering the curtailed output of Nick Drake, but acknowledgement of the artistic legacy rests on his crafted musicianship, the high esteem accorded his work by his peers, and the appreciation of a devoted, increasing audience. By the time of his death, the three albums may together have sold fewer than four thousand copies. But even in the punk era, when most folk-rock singer-songwriters were viewed suspiciously, his autodidactic, uncompromising talent was recognised and understood. His reputation has grown steadily, and record sales have increased over each decade of the last fifty years: the promotion for the BBC3 Prom rightly stated that he has reached a ‘new, cross-generational audience, many of them beguiled by his fragility and fatalism, his music's mingling of the outwardly simple and the inwardly complex’.</p><p>The author declares no conflicts of interest.</p>","PeriodicalId":13030,"journal":{"name":"Human Psychopharmacology: Clinical and Experimental","volume":"40 1","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11670808/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Psychopharmacology: Clinical and Experimental","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/hup.2916","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

The British Association for Psychopharmacology (BAP) concluded its Fiftieth Anniversary Summer Meeting in July 2024 with a plenary symposium in which BAP stalwarts glanced back and looked forward, to identify achievements in psychopharmacology since 1999 and consider likely developments in neuroscience before 2049. There was much to ponder, whilst travelling home from the University of Birmingham: and my dream-like musings continued that same evening, when the BBC Radio 3 Promenade (‘Prom’) concert broadcast was devoted solely to ‘An Orchestral Celebration’ of the music of Nick Drake, who died when aged only twenty-six, almost fifty years before, in November 1974.

Born in Rangoon, Burma (now Yangon, Myanmar), to expatriate Britons—his father worked as a Civil Engineer, his mother came from a senior Indian Civil Service family—Nicholas Rodney Drake moved with his family to the UK as a toddler, went to a preparatory boarding school, then boarded at Marlborough College, before somewhat unexpectedly scraping into Fitzwilliam College Cambridge in 1967, to read English Literature. But he left Cambridge two years later, nine months before graduation, against the advice of his tutors and family, to further his musical career: his first album, the wistful and pastoral Five Leaves Left had been released a few months earlier. A strike-delayed second album, Bryter Later, sometimes considered to be ensemble-heavy, appeared in March 1971. Both were critically acclaimed by music journalists and other musicians, but neither gained much traction with the buying public. His third album, the desolate and intermittently agitated Pink Moon, was released in February 1972, but probably sold less than its predecessors.

Characteristically reticent and often seeming aloof, he became steadily more isolated and withdrawn, possibly linked to or worsened by regular smoking of cannabis, which he started before University. He declared himself increasingly reluctant to play the live concerts which could probably have led to wider recognition and greater sales. Although he was an astonishingly adept, technically innovative guitarist and widely respected lyricist, it was more challenging for him to synchronise playing with singing. He sought company but was uncommunicative whilst in it. He neglected himself, seemed erratic and unpredictable, and sometimes had observable difficulty in sequencing tasks, such as making tea. Increasing parental concern prompted admission to the local inpatient psychiatric unit, where after a few weeks the thoughtful, compassionate consultant psychiatrist suggested their 23-year old son might suffer from simple-type schizophrenia.

Psychiatric diagnoses can be unreliable, and treatment plans are often contested. Drake himself stated that taking medication was ‘against my principles’. The well-meaning social worker attached to the local unit indicated that psychotropic medication was not as beneficial as psychotherapy, and recommended referral to a Laingian psychotherapist. By contrast, a regional specialist consultant psychiatrist recommended electroconvulsive therapy (ECT). Subsequently, an eminent London teaching hospital consultant, seeing Drake on a private basis, preferred the diagnosis of depressive illness and recommended combination treatment with amitriptyline, trifluoperazine, orphenadrine and diazepam. Drake did not attend an offered appointment with the Laing-founded Philadelphia Association. ECT was administered just once. Periods of medication adherence were accompanied by some beneficial effects, including the desire to write new material, but treatments and improvements were not sustained. He became increasingly despondent, took a large intentional overdose of diazepam (thirty-six tablets) in February 1973, and died in autumn of the following year after a substantial overdose (approximately sixty tablets) of amitriptyline: the coroner's inquest recorded a verdict of suicide ‘when suffering from a depressive illness’.

On balance, the multiple insightful observations of friends and peers featured within the forensically-detailed biography (Jack 2023) align with some important features (including negative symptoms and disorganisation) indicating a probable diagnosis of schizophrenia. His father believed this to be the case and had joined the National Schizophrenia Fellowship for support and advice: the always supportive, loving family were troubled by a sense of bewildered helplessness. They had not been made aware that amitriptyline could be fatal when taken in even small overdoses. A close friend from his University days, who subsequently became a psychiatrist, felt that regardless of diagnosis, psychotropic medication alone would have been insufficient to result in much improvement.

But regardless of favoured diagnosis, the inpatient and outpatient clinical care which Drake received was unable to arrest an inexorable decline. Current mental health services—such as early intervention in psychosis teams—would strive to provide a case-managed, community-based, multi-disciplinary approach including assertive outreach, advice against returning to cannabis smoking, psychotropic medication optimisation (perhaps involving long-acting injectable antipsychotic treatment), psychological treatment, recovery-based activities and family involvement and support. With such provisions at the time, the outcome for this troubled young man may well have been different.

An awareness of his struggle with personal mental health problems seems important when considering the curtailed output of Nick Drake, but acknowledgement of the artistic legacy rests on his crafted musicianship, the high esteem accorded his work by his peers, and the appreciation of a devoted, increasing audience. By the time of his death, the three albums may together have sold fewer than four thousand copies. But even in the punk era, when most folk-rock singer-songwriters were viewed suspiciously, his autodidactic, uncompromising talent was recognised and understood. His reputation has grown steadily, and record sales have increased over each decade of the last fifty years: the promotion for the BBC3 Prom rightly stated that he has reached a ‘new, cross-generational audience, many of them beguiled by his fragility and fatalism, his music's mingling of the outwardly simple and the inwardly complex’.

The author declares no conflicts of interest.

尼克·德雷克:一个烦恼的心灵,一个麻烦的“治疗”。
英国精神药理学协会(BAP)于2024年7月在一次全体研讨会上结束了五十周年夏季会议,BAP的坚定成员回顾了过去,展望了未来,确定了自1999年以来精神药理学的成就,并考虑了2049年之前神经科学可能的发展。在从伯明翰大学回家的路上,我有很多事情要思考:就在那天晚上,当英国广播公司第三频道的逍遥音乐会(“舞会”)的广播专门播放尼克·德雷克音乐的《管弦乐庆典》时,我的梦幻般的沉思还在继续。尼克·德雷克于1974年11月去世,享年26岁,大约50年前。尼古拉斯·罗德尼·德雷克出生于缅甸仰光(现缅甸仰光),父亲是一名土木工程师,母亲来自印度一个高级公务员家庭。尼古拉斯·罗德尼·德雷克在蹒跚学步的时候随家人移居英国,先是上了一所寄宿预科学校,然后在马尔伯勒学院寄宿,1967年意外地进入剑桥大学菲茨威廉学院学习英国文学。但两年后,也就是毕业前9个月,他不顾导师和家人的建议,离开了剑桥,去发展他的音乐事业:他的第一张专辑《剩下的五张叶子》(Five Leaves left)在几个月前发行了。他的第二张专辑《Bryter Later》于1971年3月发行,这张专辑因罢工而推迟,有时被认为是合奏曲目较多的专辑。两者都得到了音乐记者和其他音乐家的好评,但都没有得到购买大众的太多关注。他的第三张专辑《粉红月亮》(Pink Moon)于1972年2月发行,但销量可能不如前几张专辑。他性格沉默寡言,常常显得冷漠,变得越来越孤立和孤僻,这可能与他在上大学前就开始经常吸食大麻有关,或者因吸食大麻而恶化。他声称自己越来越不愿意参加现场音乐会,因为这可能会带来更广泛的认可和更高的销量。尽管他是一位技艺精湛、技术创新的吉他手和广受尊敬的词作者,但对他来说,将演奏与唱歌同步起来更具挑战性。他寻求同伴,但在同伴中却沉默寡言。他忽视了自己,似乎不稳定、不可预测,有时在安排任务时明显有困难,比如泡茶。越来越多的父母的担忧促使他们把儿子送进了当地的精神病住院病房,几周后,一位体贴、富有同情心的精神病顾问建议他们23岁的儿子可能患有单纯型精神分裂症。精神科的诊断可能不可靠,治疗方案也常常存在争议。德雷克自己说服药“违背了我的原则”。附属于当地单位的善意的社会工作者指出,精神药物治疗不如心理治疗有益,并建议转介给兰根心理治疗师。相比之下,一位地区专家咨询精神科医生推荐电休克疗法(ECT)。随后,一位著名的伦敦教学医院顾问私下给德雷克看病,更倾向于诊断为抑郁症,并建议用阿米替林、三氟拉嗪、奥非那定和地西泮联合治疗。德雷克没有参加莱恩创立的费城协会的约见。ECT只进行了一次。坚持服药的时间伴随着一些有益的影响,包括写新材料的愿望,但治疗和改善并没有持续下去。他变得越来越沮丧,于1973年2月故意过量服用地西泮(36片),并于次年秋天在大量过量服用阿米替林(大约60片)后死亡:验尸官的调查记录了“患抑郁症时”自杀的判决。总的来说,在这本法医详尽的传记(《杰克2023》)中,对朋友和同龄人的多次深刻观察与一些重要特征(包括阴性症状和紊乱)一致,表明可能患有精神分裂症。他的父亲相信这是事实,并加入了国家精神分裂症协会寻求支持和建议:这个一直支持他、充满爱的家庭被一种困惑无助的感觉所困扰。他们不知道阿米替林即使是少量过量服用也会致命。他大学时代的一位好友后来成为了一名精神病学家,他认为,不管诊断结果如何,单靠精神药物是不足以改善病情的。但不管诊断结果如何,德雷克接受的住院和门诊治疗都无法阻止他不可阻挡的衰退。 目前的精神健康服务——比如精神病小组的早期干预——将努力提供一种个案管理的、以社区为基础的、多学科的方法,包括果断的外展、建议不要再吸大麻、精神药物优化(可能包括长效注射抗精神病药物)、心理治疗、康复活动以及家庭参与和支持。如果当时有这样的规定,这个麻烦缠身的年轻人的结局很可能会有所不同。考虑到尼克·德雷克(Nick Drake)的产量减少,意识到他与个人心理健康问题的斗争似乎很重要,但对艺术遗产的认可取决于他精湛的音乐技艺,同龄人对他作品的高度尊重,以及忠诚的、不断增加的听众的欣赏。到他去世时,这三张专辑加起来可能只卖了不到四千张。但即使在朋克时代,当大多数民谣摇滚歌手兼词曲作者被怀疑的时候,他自学成才、毫不妥协的才能也得到了认可和理解。他的名声稳步上升,唱片销量在过去的五十年里每十年都在增长:BBC3舞会的宣传正确地指出,他已经获得了“新的、跨代的听众,他们中的许多人被他的脆弱和宿命论所迷惑,他的音乐融合了外在的简单和内在的复杂”。作者声明无利益冲突。
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
34
审稿时长
6-12 weeks
期刊介绍: Human Psychopharmacology: Clinical and Experimental provides a forum for the evaluation of clinical and experimental research on both new and established psychotropic medicines. Experimental studies of other centrally active drugs, including herbal products, in clinical, social and psychological contexts, as well as clinical/scientific papers on drugs of abuse and drug dependency will also be considered. While the primary purpose of the Journal is to publish the results of clinical research, the results of animal studies relevant to human psychopharmacology are welcome. The following topics are of special interest to the editors and readers of the Journal: -All aspects of clinical psychopharmacology- Efficacy and safety studies of novel and standard psychotropic drugs- Studies of the adverse effects of psychotropic drugs- Effects of psychotropic drugs on normal physiological processes- Geriatric and paediatric psychopharmacology- Ethical and psychosocial aspects of drug use and misuse- Psychopharmacological aspects of sleep and chronobiology- Neuroimaging and psychoactive drugs- Phytopharmacology and psychoactive substances- Drug treatment of neurological disorders- Mechanisms of action of psychotropic drugs- Ethnopsychopharmacology- Pharmacogenetic aspects of mental illness and drug response- Psychometrics: psychopharmacological methods and experimental design
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