Efficacy and safety of acupuncture in the treatment of Meniere's disease: a systematic review and meta-analysis.

IF 3.1 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Frontiers in Medicine Pub Date : 2024-12-11 eCollection Date: 2024-01-01 DOI:10.3389/fmed.2024.1463821
Mingjie Tang, Yinghong Li, Man Lu, Tianchen Zhang, Yanhao Ge, Jie Han, Jiqin Tang, Zhaoming Chen
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引用次数: 0

Abstract

Background: Meniere's disease (MD) is an idiopathic chronic inner ear disease that seriously impacts patients' physical and mental health. Medications may be effective for a proportion of patients, and additional effective treatments are still needed. This review aimed to evaluate the efficacy of acupuncture treatment for MD.

Methods: Eight databases were systematically searched from their inception to June 1, 2024, to identify randomized clinical trials on acupuncture treatment for MD. The Cochrane Risk of Bias 2.0 tool was used to assess the risk of bias in included studies, and meta-analysis was conducted by RevMan 5.4 and Stata 16.0 software.

Results: Six studies were included in this review. The treatment group received acupuncture or acupuncture combined with Western medicine, while the control group was treated with Western medicine. The treatment group was superior to the control group in terms of efficacy rate (RR: 1.20; 95% CI: 1.11-1.29; p < 0.0001). The treatment group reduced dizziness handicap inventory (DHI) (MD: 6.94; 95% CI: 1.58-12.30; p = 0.01), tinnitus handicap inventory (THI) (MD: 6.52; 95% CI: 0.77-12.27; p = 0.03), stuffy ear visual analog scale (VAS) (MD: 0.87; 95% CI: 0.54-1.20; p < 0.0001) and pure tone audiometry score (MD: 6.57; 95% CI: 5.62-7.51; p < 0.0001) to a greater degree than those of the control group. There were some methodological shortcomings in the included studies, including failure to implement blinding, inappropriate outcome measures, and heterogeneity of clinical interventions, such as selected acupoints, acupuncture sessions, and therapist techniques.

Conclusion: Acupuncture may improve the symptoms of vertigo, tinnitus, ear fullness and hearing loss in patients with MD. However, due to the lack of literature included in this study and methodological weaknesses like randomization, blinding, and clinical heterogeneity, more well-designed long-term follow-up RCTs are needed to evaluate the efficacy and safety of acupuncture.

Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/(CRD42024549261).

针刺治疗梅尼埃病的疗效和安全性:系统回顾和荟萃分析。
背景:梅尼埃病(Meniere's disease, MD)是一种严重影响患者身心健康的特发性慢性内耳疾病。药物可能对一部分患者有效,但仍需要额外的有效治疗。方法:系统检索8个数据库,从建立到2024年6月1日,以确定针灸治疗MD的随机临床试验。使用Cochrane风险偏倚2.0工具评估纳入研究的偏倚风险,并使用RevMan 5.4和Stata 16.0软件进行荟萃分析。结果:本综述纳入了6项研究。治疗组采用针刺或针刺结合西药治疗,对照组采用西药治疗。治疗组有效率优于对照组(RR: 1.20;95% ci: 1.11-1.29;p p = 0.01),耳鸣障碍量表(THI) (MD: 6.52;95% ci: 0.77-12.27;p = 0.03),闷耳视觉模拟量表(VAS) (MD: 0.87;95% ci: 0.54-1.20;p p 结论:针刺可改善MD患者的眩晕、耳鸣、耳胀、听力损失等症状。但由于本研究纳入文献较少,且方法存在随机化、盲法、临床异质性等缺陷,需要更多设计良好的长期随访rct来评价针刺的疗效和安全性。系统评价注册:https://www.crd.york.ac.uk/PROSPERO/(CRD42024549261)。
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来源期刊
Frontiers in Medicine
Frontiers in Medicine Medicine-General Medicine
CiteScore
5.10
自引率
5.10%
发文量
3710
审稿时长
12 weeks
期刊介绍: Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate - the use of patient-reported outcomes under real world conditions - the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines - the scientific bases for guidelines and decisions from regulatory authorities - access to medicinal products and medical devices worldwide - addressing the grand health challenges around the world
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