Monitoring Chronic Non-Cancer Pain in Denmark Over Two Decades: Prevalence, Mental Health and Loneliness

IF 3.5 2区 医学 Q1 ANESTHESIOLOGY
Ola Ekholm, Suzanne Forsyth Herling, Camilla Lykke, Svetlana Skurtveit, Aleksi Hamina, Per Sjøgren, Geana Paula Kurita
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Abstract

Background

Epidemiological surveys have monitored chronic non-cancer pain (CNCP) and investigated associated factors in Denmark for more than 20 years. This study aimed to analyse CNCP prevalence in the Danish population from 2000 to 2023 and its associations with mental health status and loneliness.

Methods

Population-based surveys were conducted between 2000 and 2023. In all waves, residents aged ≥ 16 years were randomly selected to complete a self-administered questionnaire. Samples included 10,089 respondents in 2000, 5292 in 2005, 14,330 in 2010, 13,429 in 2013, 13,050 in 2017, 10,384 in 2021 and 9303 in 2023. CNCP was defined as pain lasting ≥ 6 months. Mental status was assessed by Mental Component Summary score of Short Form-12 and severe loneliness by the Three-Item Loneliness Scale. Calibration weighting was applied to reduce potential non-response bias.

Results

The prevalence of CNCP increased steadily by 9.4 percentage points from 2000 (19.5%) to 2023 (28.9%), but with a downward tick during the COVID-19 pandemic in 2021 (25.3%). Women aged 45 years or older had the highest prevalence in all waves. Results showed a worsening of mental health over time in both individuals with and without CNCP; however, the lowest scores were reported by individuals with CNCP. Severe loneliness seemed to be a substantial problem in individuals with CNCP (17.3% in 2021).

Conclusions

In summary, CNCP was highly prevalent over the given period and associated with mental health status and severe loneliness in recent years.

Significance

This study demonstrated alarming trend on chronic non-cancer pain prevalence over time in Denmark. The high estimates of prevalence and related issues, such as mental health and severe loneliness deserve further investigation and prioritisation in the public health agenda.

监测慢性非癌症疼痛在丹麦超过二十年:患病率,心理健康和孤独。
背景:流行病学调查监测慢性非癌性疼痛(CNCP),并调查相关因素在丹麦超过20年。本研究旨在分析2000年至2023年丹麦人口中CNCP的患病率及其与心理健康状况和孤独感的关系。方法:2000 - 2023年进行人口调查。在所有的波浪中,随机选择年龄≥16岁的居民完成一份自我管理的问卷。样本包括2000年10,089人,2005年5292人,2010年14,330人,2013年13,429人,2017年13,050人,2021年10,384人,2023年9303人。CNCP定义为疼痛持续≥6个月。心理状态采用Short Form-12心理成分总结得分评估,重度孤独采用三项孤独量表评估。采用校正加权来减少潜在的无反应偏差。结果:从2000年(19.5%)到2023年(28.9%),CNCP患病率稳步上升9.4个百分点,但在2021年COVID-19大流行期间呈下降趋势(25.3%)。在所有波浪中,45岁或以上的妇女患病率最高。结果显示,随着时间的推移,患有和不患有CNCP的个体的心理健康状况都在恶化;然而,CNCP患者报告的得分最低。严重的孤独感似乎是CNCP患者的一个重大问题(2021年为17.3%)。结论:综上所述,近年来,CNCP在特定时期内高度流行,并与心理健康状况和严重孤独感有关。意义:这项研究表明,随着时间的推移,慢性非癌性疼痛在丹麦的流行趋势令人担忧。对流行率和相关问题(如心理健康和严重孤独)的高估计值得进一步调查,并在公共卫生议程中列为优先事项。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
European Journal of Pain
European Journal of Pain 医学-临床神经学
CiteScore
7.50
自引率
5.60%
发文量
163
审稿时长
4-8 weeks
期刊介绍: European Journal of Pain (EJP) publishes clinical and basic science research papers relevant to all aspects of pain and its management, including specialties such as anaesthesia, dentistry, neurology and neurosurgery, orthopaedics, palliative care, pharmacology, physiology, psychiatry, psychology and rehabilitation; socio-economic aspects of pain are also covered. Regular sections in the journal are as follows: • Editorials and Commentaries • Position Papers and Guidelines • Reviews • Original Articles • Letters • Bookshelf The journal particularly welcomes clinical trials, which are published on an occasional basis. Research articles are published under the following subject headings: • Neurobiology • Neurology • Experimental Pharmacology • Clinical Pharmacology • Psychology • Behavioural Therapy • Epidemiology • Cancer Pain • Acute Pain • Clinical Trials.
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