Mortality rates and risk factors associated with mortality in patients with stenotrophomonas maltophilia primary Bacteraemia and Pneumonia

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2024-12-21 DOI:10.1016/j.diagmicrobio.2024.116664

Mürşit Hasbek , Özlem Aldemir , Yasemin Çakır Kıymaz , Cihad Baysal , Dilara Yıldırım , Seyit Ali Büyüktuna

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Abstract

This study aims to evaluate the risk factors associated with the mortality of S. maltophilia infections. Patients aged 18 years and older with S. maltophilia infection. Patients were divided into two groups primary bacteraemia and pneumonia. Of 176 S. maltophilia infections, 85 (48.2 %) were classified as bacteremia and 91 (51.8 %) as pneumonia. The mortality rate was 56 %, with no significant difference observed between the groups. Invasive mechanical ventilation, history of carbapenem use, and high Charlson Comorbidity Index (CCI) were significantly higher in the pneumonia group. In univariate analysis, higher Acute Physiology and Chronic Health Evaluation (APACHE) II score, higher Sequential Organ Failure Assessment (SOFA) score, and use of total parenteral nutrition (TPN) were identified as independent risk factors for 28-day mortality. This study demonstrates a mortality rate of 56 % in S. maltophilia infections and provides concrete data on risk factors for mortality.

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嗜麦芽窄养单胞菌原发性菌血症和肺炎患者的死亡率和与死亡率相关的危险因素

本研究旨在评估与嗜麦芽葡萄球菌感染死亡相关的危险因素。18岁及以上嗜麦芽葡萄球菌感染患者。患者分为原发性菌血症和肺炎两组。176例嗜麦芽葡萄球菌感染中，85例（48.2%）为菌血症，91例（51.8%）为肺炎。死亡率为56%，两组间无显著差异。肺炎组有创机械通气、碳青霉烯类药物使用史、高Charlson合并症指数（CCI）显著增高。在单因素分析中，较高的急性生理和慢性健康评估（APACHE） II评分、较高的顺序器官衰竭评估（SOFA）评分和使用全肠外营养（TPN）被确定为28天死亡率的独立危险因素。本研究表明嗜麦芽葡萄球菌感染的死亡率为56%，并提供了死亡危险因素的具体数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.