The associations between dietary omega-6, omega-3, and omega 6 to omega 3 ratio fatty acids and hypertension risk among adults: A prospective cohort study.

IF 2.9 Q3 NUTRITION & DIETETICS

Clinical nutrition ESPEN Pub Date : 2024-12-26 DOI:10.1016/j.clnesp.2024.12.022

Ebrahim Shakiba, Yahya Pasdar, Sara Ebrahimi-Mousavi, Farid Najafi, Amir Saber, Mohammad Hossein Shakiba, Amir Bagheri

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引用次数: 0

Abstract

Background and aims: Previous studies have yielded mixed results on the connection between dietary omega-3 and omega-6 intakes and the risk of hypertension (HTN) incidents. Therefore, we conducted a study to survey the connection between baseline dietary intake of omega-3, omega-6, and omega-6 to omega 3 (omega-6/3) fatty acids (FA) and the risk of hypertension.

Methods: We conducted a prospective cohort study and assessed dietary intake through a 118-item food frequency questionnaire (FFQ). To determine the relationship between dietary omega-3, omega-6, and omega-6/3 ratio intake and the risk of developing hypertension, we applied Cox proportional hazards analysis to determine hazard ratios (HR) and 95 % confidence intervals (CIs).

Results: After following 7359 participants who did not have hypertension at the beginning of the study for 6.4 ± 1.33 years, we identified 597 new cases of hypertension (8.11 %). Our analysis, which controlled for all confounders, did not identify any significant link among the highest versus lowest quartile of dietary omega-3 intake (HR: 0.87, 95 % CI: 0.63, 1.18; P trend: 0.34), omega-6 intake (HR: 1.04; 95 % CI: 0.81, 1.34; P trend: 0.82), and omega-6/3 ratio intakes (HR: 1.06, 95 % CI: 0.82, 1.36; P trend: 0.66) and HTN risk.

Conclusions: To sum up, our study revealed that dietary omega-3, omega-6, and omega-6/3 ratio were not associated with the hypertension risk.

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来源期刊

Clinical nutrition ESPEN NUTRITION & DIETETICS-

CiteScore

4.90

自引率

3.30%

发文量

512

期刊介绍： Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.