Natural-derived porous nanocarriers for the delivery of essential oils

IF 4 2区 医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE
Hongxin CHEN , Xiaoyu SU , Yijuan LUO , Yan LIAO , Fengxia WANG , Lizhen HUANG , Aiguo FAN , Jing LI , Pengfei YUE
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Abstract

Essential oils (EOs) are natural, volatile substances derived from aromatic plants. They exhibit multiple pharmacological effects, including antibacterial, anticancer, anti-inflammatory, and antioxidant properties, with broad application prospects in health care, food, and agriculture. However, the instability of volatile components, which are susceptible to deterioration under light, heat, and oxygen exposure, as well as limited water solubility, have significantly impeded the development and application of EOs. Porous nanoclays are natural clay minerals with a layered structure. They possess unique structural characteristics such as large pore size, regular distribution, and tunable particle size, which are extensively utilized in drug delivery, adsorption separation, reaction catalysis, and other fields. Natural-derived porous nanoclays have garnered considerable attention for the encapsulation and delivery of EOs. This review comprehensively summarizes the structure, types, and properties of natural-derived porous nanoclays, focusing on the structural characteristics of porous nanoclays such as montmorillonite, palygorskite, halloysite, kaolinite, vermiculite, and natural zeolite. It also examines research advances in their delivery of EOs and explores engineering strategies to enhance the delivery of EOs by natural-derived porous nanoclays. Finally, various applications of natural-derived porous nanoclays for EOs in antibacterial, food preservation, repellent, and insecticide aspects are presented, providing a reference for the development and application of EOs.
天然衍生的用于输送精油的多孔纳米载体。
精油(EOs)是从芳香植物中提取的天然挥发性物质。具有抗菌、抗癌、抗炎、抗氧化等多种药理作用,在保健、食品、农业等领域具有广阔的应用前景。然而,挥发性成分的不稳定性,在光、热、氧暴露下容易变质,以及有限的水溶性,严重阻碍了EOs的开发和应用。多孔纳米粘土是具有层状结构的天然粘土矿物。它们具有孔径大、分布规则、粒度可调等独特的结构特点,广泛应用于药物输送、吸附分离、反应催化等领域。天然衍生的多孔纳米粘土已经引起了相当大的关注,用于EOs的封装和输送。本文综述了天然多孔纳米粘土的结构、类型和性质,重点介绍了蒙脱土、坡高岭土、高岭土、高岭土、蛭石和天然沸石等多孔纳米粘土的结构特征。它还检查了他们的研究进展,在交付EOs和探索工程策略,以提高天然衍生的多孔纳米粘土的交付EOs。最后介绍了天然多孔纳米粘土在抗菌、食品保鲜、驱避、杀虫等方面的应用,为环氧树脂的开发和应用提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Chinese Journal of Natural Medicines
Chinese Journal of Natural Medicines INTEGRATIVE & COMPLEMENTARY MEDICINE-PHARMACOLOGY & PHARMACY
CiteScore
7.50
自引率
4.30%
发文量
2235
期刊介绍: The Chinese Journal of Natural Medicines (CJNM), founded and sponsored in May 2003 by China Pharmaceutical University and the Chinese Pharmaceutical Association, is devoted to communication among pharmaceutical and medical scientists interested in the advancement of Traditional Chinese Medicines (TCM). CJNM publishes articles relating to a broad spectrum of bioactive natural products, leading compounds and medicines derived from Traditional Chinese Medicines (TCM). Topics covered by the journal are: Resources of Traditional Chinese Medicines; Interaction and complexity of prescription; Natural Products Chemistry (including structure modification, semi-and total synthesis, bio-transformation); Pharmacology of natural products and prescription (including pharmacokinetics and toxicology); Pharmaceutics and Analytical Methods of natural products.
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