Continuous Glucose Monitoring Underreports Blood Glucose During a Simulated Ultraendurance Run in Eumenorrheic Female Runners.

IF 3.5 2区 医学 Q1 PHYSIOLOGY
Andrew Dole, Stacy Sims, Han Gan, Nic Gill, Martyn Beaven
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引用次数: 0

Abstract

Purpose: Continuous-glucose-monitoring (CGM) sensors provide near-real-time glucose data and have been introduced commercially as a tool to inform nutrition decisions. The aim of this pilot study was to explore how factors such as the menstrual phase, extended running duration, and carbohydrates affect CGM outcomes among trained eumenorrheic females in an outdoor simulated ultraendurance running event.

Methods: Twelve experienced female ultrarunners (age 39 [6] y) participated in this crossover study. Participants completed an ultraendurance simulation run of 4 hours in the midfollicular and midluteal phases of their menstrual cycle, which consisted of a 3-hour fasted outdoor run (FASTED) followed by a 1-hour treadmill run (TREAD), where 3 standardized 20-g oral glucose doses were provided.

Results: Using a mixed linear model, the menstrual phase was statistically significant for differences in glucose measurements from CGM compared with capillary glucose sampling during TREAD (P = .02) but not FASTED. Additionally, the CGM sensor reported glucose levels with an average of -0.43 mmol·L-1 (95% CI, - 0.86 to -0.005) and -1.02 mmol·L-1 (95% CI, -1.63 to -0.42) lower in fasted and fed scenarios, respectively, when compared with capillary glucose.

Conclusion: CGM underreports capillary glucose during fasted and fed exercise. Factors contributing to this underreporting between the sampling methods (CGM vs capillary) were dependent on a combination of exogenous glucose availability, individual biological differences, and the menstrual phase.

连续血糖监测低报模拟经期女性跑步者的超耐力跑期间的血糖。
目的:连续血糖监测(CGM)传感器提供近实时的血糖数据,并已作为一种告知营养决策的商业工具引入。本初步研究的目的是探讨经期、延长跑步时间和碳水化合物等因素如何影响经训练的痛经女性在户外模拟超耐力跑步比赛中的CGM结果。方法:12名有经验的女性超跑者(年龄39 ~ 90岁)参与了这项交叉研究。参与者在月经周期的卵泡中期和黄体中期完成了4小时的超耐力模拟跑,其中包括3小时的禁食户外跑(fasted),然后是1小时的跑步机跑(TREAD),其中提供了3个标准化的20克口服葡萄糖剂量。结果:使用混合线性模型,月经期CGM测量的葡萄糖与毛细血管葡萄糖取样在TREAD期间的差异有统计学意义(P = .02),但在FASTED期间没有差异。此外,与毛细血管血糖相比,CGM传感器报告的血糖水平在禁食和进食情况下分别平均降低-0.43 mmol·L-1 (95% CI, - 0.86至-0.005)和-1.02 mmol·L-1 (95% CI, -1.63至-0.42)。结论:CGM少报了空腹和空腹运动时的毛细血管血糖。导致两种采样方法(CGM vs毛细血管)少报的因素取决于外源性葡萄糖可用性、个体生物学差异和月经期的组合。
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来源期刊
CiteScore
5.80
自引率
12.10%
发文量
199
审稿时长
6-12 weeks
期刊介绍: The International Journal of Sports Physiology and Performance (IJSPP) focuses on sport physiology and performance and is dedicated to advancing the knowledge of sport and exercise physiologists, sport-performance researchers, and other sport scientists. The journal publishes authoritative peer-reviewed research in sport physiology and related disciplines, with an emphasis on work having direct practical applications in enhancing sport performance in sport physiology and related disciplines. IJSPP publishes 10 issues per year: January, February, March, April, May, July, August, September, October, and November.
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