Idiopathic Vanishing Bile Duct Syndrome in a Young Female: A Case Report.

Min Ji Kim, Hyun Myung Cho, Young Mi Hong, Ki Tae Yoon
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引用次数: 0

Abstract

Vanishing bile duct syndrome (VBDS) is characterized by the progressive loss and destruction of the intrahepatic bile ducts, leading to bile stasis and associated symptoms such as jaundice. This condition is commonly associated with drug side effects, infections, neoplasms, and autoimmune diseases, but the precise mechanism of its development is unclear. Although VBDS can be diagnosed based on the patient's symptoms and disease progression, a liver biopsy is essential for confirmation, and the prognosis can vary significantly. This paper presents a rare case of a young female patient diagnosed with idiopathic VBDS after undergoing a liver biopsy to investigate unexplained jaundice. The patient's liver function improved partially after an ursodeoxycholic acid and prednisolone treatment.

年轻女性特发性胆管消失综合征1例报告。
胆管消失综合征(VBDS)的特点是肝内胆管的逐渐丧失和破坏,导致胆汁淤积和相关症状,如黄疸。这种情况通常与药物副作用、感染、肿瘤和自身免疫性疾病有关,但其发展的确切机制尚不清楚。虽然VBDS可以根据患者的症状和疾病进展进行诊断,但肝活检是确诊的必要条件,而且预后差异很大。本文报告一例罕见的年轻女性患者在接受肝脏活检以调查不明原因的黄疸后被诊断为特发性VBDS。在熊去氧胆酸和强的松龙治疗后,患者肝功能部分改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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