Comparison of Chlamydia trachomatis Seroprevalence and Risk Factors for Infection Among Women by Gender/Sex of Sex Partner, United States, 2013-2016.

IF 2.4 4区医学 Q3 INFECTIOUS DISEASES

Sexually transmitted diseases Pub Date : 2024-12-24 DOI:10.1097/OLQ.0000000000002134

Keely S Paris, Christine M Khosropour, Jennifer E Balkus, Mary Bridget Waters, Kristen M Kreisel, Lisa E Manhart

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引用次数: 0

Abstract

Objectives: Women who report sex with women are thought to have lower risk for Chlamydia trachomatis (CT) infection than women who report sex with men only (WSM-only), but comparisons of lifetime burden are limited.

Methods: Among 1,418 sexually-experienced women aged 18-39 years participating in the National Health and Nutrition Examination Survey (2013-2016), we estimated weighted CT seroprevalence and Wald-based 95% confidence intervals (CI) in women who reported ever having sex with a woman (all reported having sex with men also) (WSWM) compared to WSM-only. We defined seropositivity as detection of Pgp3 antibodies and used stratified Poisson regression with robust standard errors to estimate prevalence ratios.

Results: Over half (58.3%) were White non-Hispanic; 16.2% were WSWM. WSWM were somewhat younger (mean = 27.8 vs. 29.0 years, p = 0.07), younger at sexual debut (mean = 15.6 vs. 17.5 years, p < 0.001), and had more lifetime male sexual partners (mean = 15.9 vs. 6.4, p < 0.001) than WSM-only. Weighted CT seroprevalence was 38.9% (95%CI = 30.4-47.4) in WSWM and 28.6% (95%CI = 24.4-32.9) in WSM-only. Correlates of higher CT seroprevalence in both groups were Black non-Hispanic race/ethnicity, Hispanic ethnicity, and CT infection in the prior year. Having ≥5 lifetime male partners compared to 1-2 partners was associated with higher seroprevalence among WSWM (PR = 4.5; 95%CI = 1.77-11.44) and WSM-only (PR = 2.7; 95%CI = 1.87-3.69). Among WSWM, bisexual identity was associated with lower seroprevalence. Among WSM-only, low income and younger age at sexual debut were associated with higher seroprevalence.

Conclusion: Lifetime CT burden was higher in WSWM than WSM-only. Number of lifetime male partners was the strongest predictor of seropositivity for WSWM.

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2013-2016年美国不同性别/性伴侣女性沙眼衣原体血清阳性率及感染危险因素比较

目的：报告与女性发生性行为的女性被认为感染沙眼衣原体（CT）的风险低于仅报告与男性发生性行为的女性（WSM-only），但终生负担的比较有限。方法：在参与国家健康与营养调查（2013-2016）的1418名年龄在18-39岁之间有过性经验的女性中，我们估计了与仅wsm相比，报告曾与女性发生过性行为（所有报告也与男性发生过性行为）的女性（WSWM）的加权CT血清患病率和基于wald的95%置信区间（CI）。我们将血清阳性定义为检测到Pgp3抗体，并使用具有稳健标准误差的分层泊松回归来估计患病率。结果：超过一半（58.3%）是非西班牙裔白人；16.2%为WSWM。WSWM比单纯wsm更年轻（平均27.8岁比29.0岁，p = 0.07），更年轻的初次性行为（平均15.6岁比17.5岁，p < 0.001），并且有更多的终生男性性伴侣（平均15.9岁比6.4岁，p < 0.001）。WSWM的加权CT血清阳性率为38.9% (95%CI = 30.4-47.4)，单纯wsm的加权CT血清阳性率为28.6% （95%CI = 24.4-32.9）。两组中较高的CT血清阳性率与非西班牙裔黑人、西班牙裔黑人和前一年的CT感染相关。与1-2名男性伴侣相比，拥有≥5名男性伴侣与WSWM中更高的血清患病率相关(PR = 4.5；95%CI = 1.77-11.44)和仅wsm (PR = 2.7；95%ci = 1.87-3.69)。在WSWM中，双性恋身份与较低的血清阳性率相关。在只有wsm的人群中，低收入和较年轻的初次性行为年龄与较高的血清患病率相关。结论：WSWM患者的终身CT负担高于单纯wsm患者。终生男性伴侣的数量是WSWM血清阳性的最强预测因子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sexually transmitted diseases 医学-传染病学

CiteScore

4.00

自引率

16.10%

发文量

289

审稿时长

3-8 weeks

期刊介绍： Sexually Transmitted Diseases, the official journal of the American Sexually Transmitted Diseases Association, publishes peer-reviewed, original articles on clinical, laboratory, immunologic, epidemiologic, behavioral, public health, and historical topics pertaining to sexually transmitted diseases and related fields. Reports from the CDC and NIH provide up-to-the-minute information. A highly respected editorial board is composed of prominent scientists who are leaders in this rapidly changing field. Included in each issue are studies and developments from around the world.