The fraction of cancer attributable to modifiable risk factors in Turkey in 2018.

IF 5.7 2区 医学 Q1 ONCOLOGY
Busra Tozduman, Gul Ergor
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引用次数: 0

Abstract

Cancer is the second leading cause of death in Turkey, with nearly one in six deaths attributed to the disease. In 2018, Turkey recorded 211,273 new cancer cases. Many cancers are linked to modifiable lifestyle risk factors, such as tobacco use, alcohol consumption, obesity, and inadequate diet and physical activity. Modifying these risk factors could potentially prevent 30%-50% of cancer cases and deaths. This study aims to estimate the population attributable fraction (PAF) of cancer cases and deaths due to various modifiable risk factors in Turkey. Modifiable cancer risk factors were identified as smoking, infections, obesity, physical inactivity, alcohol consumption, inadequate intake of fruits, vegetables, fiber, and calcium. Data on exposure prevalence and cancer incidence were sourced from national surveys and reports. Relative risks (RRs) were obtained from global studies. PAFs were calculated using Levin's equation, accounting for overlaps between risk factors. In 2018, 32% of the cancer cases were attributable to lifestyle risk factors. Smoking was the most significant factor, accounting for 28.4% of cases in men, while high BMI was the leading factor in women, contributing to 11.5% of cases. Lifestyle risk factors were responsible for 41.6% of cancer deaths, with smoking being the leading cause. Lifestyle risk factors contribute significantly to cancer incidence and mortality in Turkey. Prioritizing interventions to reduce tobacco use and obesity could substantially lower the cancer burden. These results are crucial for developing effective cancer prevention strategies and informing public health policies.

2018年土耳其可改变风险因素导致的癌症比例。
癌症是土耳其的第二大死因,近六分之一的死亡归因于该疾病。2018年,土耳其记录了211,273例新的癌症病例。许多癌症与可改变的生活方式风险因素有关,如吸烟、饮酒、肥胖、饮食和体育活动不足。改变这些危险因素有可能预防30%-50%的癌症病例和死亡。本研究旨在估计土耳其由各种可改变的危险因素引起的癌症病例和死亡的人口归因比例(PAF)。可改变的癌症风险因素包括吸烟、感染、肥胖、缺乏运动、饮酒、水果、蔬菜、纤维和钙摄入不足。有关接触流行率和癌症发病率的数据来自国家调查和报告。相对危险度(rr)来自全球研究。考虑到风险因素之间的重叠,使用莱文方程计算paf。2018年,32%的癌症病例可归因于生活方式风险因素。吸烟是最重要的因素,占男性病例的28.4%,而高BMI是女性的主要因素,占11.5%。41.6%的癌症死亡是由生活方式风险因素造成的,其中吸烟是主要原因。生活方式风险因素对土耳其的癌症发病率和死亡率有重大影响。优先考虑减少烟草使用和肥胖的干预措施可以大大降低癌症负担。这些结果对于制定有效的癌症预防战略和为公共卫生政策提供信息至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
13.40
自引率
3.10%
发文量
460
审稿时长
2 months
期刊介绍: The International Journal of Cancer (IJC) is the official journal of the Union for International Cancer Control—UICC; it appears twice a month. IJC invites submission of manuscripts under a broad scope of topics relevant to experimental and clinical cancer research and publishes original Research Articles and Short Reports under the following categories: -Cancer Epidemiology- Cancer Genetics and Epigenetics- Infectious Causes of Cancer- Innovative Tools and Methods- Molecular Cancer Biology- Tumor Immunology and Microenvironment- Tumor Markers and Signatures- Cancer Therapy and Prevention
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