Sudarshan Kriya Yoga Promotes Telomere Elongation: A Pilot Study.

IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE
Vinod Mony, Saumya Subramanian, Divya Kanchibhotla
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引用次数: 0

Abstract

Background: Telomere length has been identified as a marker for biological aging and stressful body states. Mind-body interventions for stress reduction such as meditation, yoga, and pranayama have been previously tested to evaluate their efficacy in restricting telomere shortening.

Primary study objective: In this study, the effect of Sudarshan Kriya Yoga (SKY) is investigated for its influence on telomere length.

Methods: Isolating the genomic DNA from the blood, relative telomere length was found using a quantitative PCR method for the SKY intervention group and a control group. Telomere maintenance gene expression was assessed from a microarray gene expression dataset.

Setting: Sri Sri Institute for Advanced Research, Bangalore.

Participants: Employees, working at a corporate organization were the participants of this study. 11 individuals were enrolled in the intervention group while 5 were enrolled in the control group.

Intervention: The integrated yoga-meditation practice, Sudarshan Kriya Yoga (SKY).

Primary outcome measures: The relative telomere length and the expression of telomere maintenance genes from the genomic DNA isolated from the participants' blood samples.

Results: Telomere length after SKY increased significantly compared to the baseline. However, in the controls, the corresponding change was insignificant. The telomere maintenance gene expression analysis reveals an intervention response conducive to telomere length extension at the molecular level.

Conclusion: The extension of telomere length after SKY underscores its efficacy in stress reduction and improved health-span.

苏达山克里亚瑜伽促进端粒延长:一项初步研究。
背景:端粒长度已被确定为生物老化和应激身体状态的标志。身心干预减轻压力,如冥想、瑜伽和调息,之前已经测试过,以评估它们在限制端粒缩短方面的功效。主要研究目的:本研究探讨苏达山克里亚瑜伽(SKY)对端粒长度的影响。方法:从血液中分离基因组DNA,采用定量PCR方法对SKY干预组和对照组进行相对端粒长度测定。端粒维持基因表达通过微阵列基因表达数据集进行评估。地点:班加罗尔Sri Sri高级研究所。参与者:在公司组织工作的员工是本研究的参与者。干预组有11人对照组有5人。干预:综合瑜伽冥想练习,苏达山克里亚瑜伽(SKY)。主要结果测量:相对端粒长度和端粒维持基因的表达从参与者的血液样本中分离的基因组DNA。结果:与基线相比,SKY后端粒长度明显增加。然而,在对照组中,相应的变化不显著。端粒维持基因表达分析揭示了在分子水平上有利于端粒长度延长的干预反应。结论:SKY术后端粒长度的延长强调了其减轻应激和提高健康寿命的作用。
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来源期刊
Alternative therapies in health and medicine
Alternative therapies in health and medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
0.90
自引率
0.00%
发文量
219
期刊介绍: Launched in 1995, Alternative Therapies in Health and Medicine has a mission to promote the art and science of integrative medicine and a responsibility to improve public health. We strive to maintain the highest standards of ethical medical journalism independent of special interests that is timely, accurate, and a pleasure to read. We publish original, peer-reviewed scientific articles that provide health care providers with continuing education to promote health, prevent illness, and treat disease. Alternative Therapies in Health and Medicine was the first journal in this field to be indexed in the National Library of Medicine. In 2006, 2007, and 2008, ATHM had the highest impact factor ranking of any independently published peer-reviewed CAM journal in the United States—meaning that its research articles were cited more frequently than any other journal’s in the field. Alternative Therapies in Health and Medicine does not endorse any particular system or method but promotes the evaluation and appropriate use of all effective therapeutic approaches. Each issue contains a variety of disciplined inquiry methods, from case reports to original scientific research to systematic reviews. The editors encourage the integration of evidence-based emerging therapies with conventional medical practices by licensed health care providers in a way that promotes a comprehensive approach to health care that is focused on wellness, prevention, and healing. Alternative Therapies in Health and Medicine hopes to inform all licensed health care practitioners about developments in fields other than their own and to foster an ongoing debate about the scientific, clinical, historical, legal, political, and cultural issues that affect all of health care.
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