Black Carbon Air Pollution and Incident Mortality among the Advance-Aged Adults in China: A Prospective Cohort Study

Anna Zhu, Haidong Kan, Xiaoming Shi, Yi Zeng, John S Ji
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Abstract

Background We aimed to assess associations between black carbon (BC) and non-accidental mortality among advance-aged adults in China. Methods We conducted a prospective cohort study in 22 provinces of Chinese Longitudinal Healthy Longevity Survey. We calculated concentrations of 3-year average BC, fine particulate matter (PM2.5), and other PM2.5 components (SO42-, NO3-, NH4+, and organic matter) at individual levels. We used Cox proportional hazards models to assess dose-response BC exposure on non-accidental mortality, adjusted for total PM2.5, green space, temperature, humidity, and demographic covariates. Results We studied 12,873 participants, with a median age of 88 years and 57.4% females. For a median follow-up of 4 years, we observed 7,426 mortality events. The mean 3-year average BC and total PM2.5 exposure concentrations were 3.49 and 66.97 μg/m3, respectively. An increase of 1 μg/m3 in BC was associated with a 39% increase in mortality risks (HR: 1.39, 95% CI: 1.36, 1.43), notably higher than the corresponding increase in mortality risks linked to total PM2.5 (HR: 1.003, 95% CI: 1.002, 1.004). The stratified analyses show that people living in rural areas, with lower social and leisure activity index, and lower physical activity, were at greater risk from BC exposure. Conclusions BC is a strong predictor of mortality, with a higher effect estimate compared with total PM2.5 and other PM2.5 components, particularly in rural populations. While total PM2.5 has been a target indicator of clean air policy interventions, our results indicate that BC concentration should be routinely measured, reported, and studied to improve public health.
黑碳空气污染与中国老年人死亡率:一项前瞻性队列研究
背景:我们旨在评估中国老年人黑碳(BC)与非意外死亡率之间的关系。方法对中国22个省份的健康寿命纵向调查进行前瞻性队列研究。我们计算了3年平均BC浓度、细颗粒物(PM2.5)和其他PM2.5成分(SO42-、NO3-、NH4+和有机物)的个体水平。我们使用Cox比例风险模型来评估剂量-反应BC暴露对非意外死亡率的影响,并根据PM2.5总量、绿地面积、温度、湿度和人口统计学协变量进行调整。我们研究了12873名参与者,中位年龄为88岁,其中57.4%为女性。在平均4年的随访中,我们观察到7426例死亡事件。3年平均BC和PM2.5暴露浓度分别为3.49和66.97 μg/m3。BC每增加1 μg/m3,死亡风险增加39% (HR: 1.39, 95% CI: 1.36, 1.43),显著高于与总PM2.5相关的死亡风险相应增加(HR: 1.003, 95% CI: 1.002, 1.004)。分层分析表明,生活在农村地区的人,社会和休闲活动指数较低,体力活动较少,接触BC的风险更大。结论:BC是死亡率的一个强有力的预测因子,与PM2.5总量和其他PM2.5成分相比,特别是在农村人群中,具有更高的效应估计。虽然PM2.5总量一直是清洁空气政策干预的目标指标,但我们的研究结果表明,为了改善公众健康,应该定期测量、报告和研究BC浓度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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