Postoperative Nausea and Vomiting After Minor Oral Surgery: A Retrospective Cohort Study.

Anesthesia progress Pub Date : 2024-12-04 DOI:10.2344/611198
Fumika Ogata, Tina Nakamura, Hiroshi Hoshijima, Katsushi Doi, Hiroshi Nagasaka, Tsutomu Mieda
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Abstract

Objective: This study aimed to determine whether PONV rates differed over time and to identify potential differences in PONV risk factors for oral surgery patients undergoing general inhalational anesthesia (IA) or propofol-based total intravenous anesthesia (TIVA).

Methods: This retrospective cohort study included patients between 16 and 85 years of age and who received intubated general anesthesia with either IA or TIVA for minor oral surgery between January 2021 and July 2022. Primary outcomes were PONV overall (onset at 0-24 hours), early (onset at 0-2 hours), and late (onset at 2-24 hours). Known PONV risk factors as identified from existing literature were included for analysis.

Results: Data were obtained from 188 patients. A total of 41 (21.8%) patients developed overall PONV, 35 patients (18.6%) had early PONV, and 14 patients (7.4%) had late PONV. Any PONV that occurred across 2 periods was categorized in each period. IA compared with TIVA had higher overall PONV (29.6% vs 13.3%; P = .008) and early PONV (25.5% vs 11.1%; P = .034). Female sex and increased Apfel scores were associated with increased overall, early, and late PONV. Per multivariate analysis, females were 2.5 to 6 times higher than males to have overall, early, and late PONV (P < .05), and IA was 3 times higher than TIVA to have overall and early, but not late, PONV (P < .05).

Conclusion: Our results suggested that the method of anesthesia may impact the incidence of overall and early PONV and that female sex and increase Apfel scores correlated with increased PONV through all times.

小口腔手术后恶心呕吐:一项回顾性队列研究。
目的:本研究旨在确定接受全身吸入麻醉(IA)或基于异丙酚的全静脉麻醉(TIVA)的口腔手术患者PONV发生率是否随时间而变化,并确定PONV危险因素的潜在差异。方法:本回顾性队列研究纳入了2021年1月至2022年7月期间接受IA或TIVA插管全身麻醉进行小口腔手术的16至85岁患者。主要结局为总PONV(发病0-24小时)、早期(发病0-2小时)和晚期(发病2-24小时)。从现有文献中确定的已知PONV危险因素纳入分析。结果:188例患者资料。共有41例(21.8%)患者发展为整体PONV, 35例(18.6%)为早期PONV, 14例(7.4%)为晚期PONV。任何发生在两个时期的PONV都在每个时期进行分类。与TIVA相比,IA具有更高的总体PONV (29.6% vs 13.3%;P = 0.008)和早期PONV (25.5% vs 11.1%;P = .034)。女性性别和Apfel评分的增加与总体、早期和晚期PONV的增加有关。多因素分析显示,女性发生全面、早期和晚期PONV的概率是男性的2.5 ~ 6倍(P < 0.05), IA发生全面、早期和晚期PONV的概率是TIVA的3倍(P < 0.05)。结论:麻醉方式可能影响整体及早期PONV的发生率,且女性及Apfel评分升高均与PONV升高相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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