Morphometry, variations, and histogenesis of umbilical vein, portal sinus, and ductus venosus in human fetal liver: an anatomical study.

IF 1.4 4区医学 Q2 Medicine

Surgical and Radiologic Anatomy Pub Date : 2024-12-23 DOI:10.1007/s00276-024-03543-2

Harika Gali, Vrinda Hari Ankolekar

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引用次数: 0

Abstract

Purpose: Anatomical research on fetal liver venous systems is scarce. This study presents variations, morphometric, and histogenesis data through cadaveric study which can aid prenatal radiological analysis.

Materials and methods: 10% formalin embalmed 16 fetuses (8-second trimester, 8-third trimester) were utilized. Morphometric and histological evaluation of the umbilical vein, portal sinus, and ductus venosus were done. Variations were noted. Descriptive statistics, ratio, correlation, and regression were used for data analysis.

Result: A positive correlation of morphometric variables with gestational age is observed. An intra-hepatic portal shunt is observed connecting the left hepatic vein and portal sinus. In one case ductus venosus arose from the medial end of portal sinus and is not in continuity with the umbilical vein. Umbilical and portal sinus presents tunica intima, tunica media, and adventitia. There is an increase in smooth muscle fibers in tunica media from the second to third trimester. Ductus venosus consists of three parts- inlet, outlet, and isthmus. The wall of ductus venosus showed tunica intima and tunica adventitia.

Conclusion: This study records the variations of the umbilical vein, portal sinus, and ductus venosus. Knowledge of variations, morphometry, and histogenesis of these veins is essential to distinguish clinical variations from conditions such as agenesis of ductus venosus, persistence of the right umbilical vein, and congenital portal-systemic shunts.

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人胎儿肝脏脐静脉、门静脉窦和静脉导管的形态学、变异和组织发生：一项解剖学研究。

目的：胎儿肝静脉系统的解剖学研究较少。本研究通过尸体研究提供变异、形态计量学和组织发生数据，有助于产前放射学分析。材料与方法：采用10%福尔马林防腐处理的16例胎儿（孕中期8、孕晚期8）。对脐静脉、门静脉窦和静脉导管进行形态学和组织学评价。注意到变化。采用描述性统计、比值、相关、回归等方法进行数据分析。结果：形态学变量与胎龄呈正相关。肝内门静脉分流连接左肝静脉和门静脉窦。1例静脉导管起源于门静脉窦内侧端，与脐静脉不连续。脐窦和门静脉窦有内膜、中膜和外膜。从妊娠中期到晚期，中膜中平滑肌纤维增多。静脉导管由入口、出口和峡部三部分组成。静脉导管壁呈内膜和外膜。结论：本研究记录了脐静脉、门静脉窦和静脉导管的变化。了解这些静脉的变异、形态和组织发生对于区分临床变异与静脉导管发育不全、右脐静脉持续存在和先天性门静脉-全身分流等情况至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgical and Radiologic Anatomy Medicine-Pathology and Forensic Medicine

CiteScore

2.40

自引率

14.30%

发文量

期刊介绍： Anatomy is a morphological science which cannot fail to interest the clinician. The practical application of anatomical research to clinical problems necessitates special adaptation and selectivity in choosing from numerous international works. Although there is a tendency to believe that meaningful advances in anatomy are unlikely, constant revision is necessary. Surgical and Radiologic Anatomy, the first international journal of Clinical anatomy has been created in this spirit. Its goal is to serve clinicians, regardless of speciality-physicians, surgeons, radiologists or other specialists-as an indispensable aid with which they can improve their knowledge of anatomy. Each issue includes: Original papers, review articles, articles on the anatomical bases of medical, surgical and radiological techniques, articles of normal radiologic anatomy, brief reviews of anatomical publications of clinical interest. Particular attention is given to high quality illustrations, which are indispensable for a better understanding of anatomical problems. Surgical and Radiologic Anatomy is a journal written by anatomists for clinicians with a special interest in anatomy.