{"title":"Left ventricular wall thickness discrepancies at end-diastole and mid-diastole: Reference values for cardiac CT.","authors":"Jiao Chen, Dan Zhao, Mengyu Xie, Jinqiu Wang, Chao Chen, Jinwen Wu, Ying Zhou","doi":"10.1016/j.clinimag.2024.110390","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To investigate differences in left ventricular wall thickness (LVWT) measurements between end-diastole and mid-diastole using cardiac computed tomography (CCT) and establish LVWT reference values stratified by phase, sex, and region.</p><p><strong>Methods: </strong>Subjects who underwent CCT without a history of cardiovascular disease or risk factors were retrospectively included between 2021 and 2024. LVWT was manually measured in each segment according to the American Heart Association's 17-segment model at end-diastole and mid-diastole. Regional LVWT was calculated as the average value of relevant segments.</p><p><strong>Results: </strong>The study included 187 subjects with a mean age of 51 ± 11 years, including 77 (41 %) men. Global LVWT was lower at end-diastole than at mid-diastole (5.7 ± 0.8 vs. 6.5 ± 0.9 mm, P < 0.001). Each segmental LVWT correlated significantly between end-diastole and mid-diastole (Pearson's correlation coefficient: 0.79-0.87). Segment 2 was thickest (8.1 ± 1.5 mm at end-diastole and 9.1 ± 1.7 mm at mid-diastole). LVWT was greater in men than in women (all P < 0.001). The upper limits of LVWT were 9.9 mm for women and 11.7 mm for men at end-diastole, and 11.8 mm for women and 13.1 mm for men at mid-diastole. LVWT progressively thinned from the base to the apex. Apical LVWT measured on short-axis and long-axis showed a small but statistically significant difference, particularly in Segment 16.</p><p><strong>Conclusion: </strong>This study provides CCT reference values for LVWT at end-diastole and mid-diastole. Mid-diastolic LVWT was slightly greater than end-diastolic LVWT, with a statistically significant difference. Normal LVWT was greater in men than in women, with regional variations observed in both phases.</p>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"118 ","pages":"110390"},"PeriodicalIF":1.8000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.clinimag.2024.110390","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/14 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To investigate differences in left ventricular wall thickness (LVWT) measurements between end-diastole and mid-diastole using cardiac computed tomography (CCT) and establish LVWT reference values stratified by phase, sex, and region.
Methods: Subjects who underwent CCT without a history of cardiovascular disease or risk factors were retrospectively included between 2021 and 2024. LVWT was manually measured in each segment according to the American Heart Association's 17-segment model at end-diastole and mid-diastole. Regional LVWT was calculated as the average value of relevant segments.
Results: The study included 187 subjects with a mean age of 51 ± 11 years, including 77 (41 %) men. Global LVWT was lower at end-diastole than at mid-diastole (5.7 ± 0.8 vs. 6.5 ± 0.9 mm, P < 0.001). Each segmental LVWT correlated significantly between end-diastole and mid-diastole (Pearson's correlation coefficient: 0.79-0.87). Segment 2 was thickest (8.1 ± 1.5 mm at end-diastole and 9.1 ± 1.7 mm at mid-diastole). LVWT was greater in men than in women (all P < 0.001). The upper limits of LVWT were 9.9 mm for women and 11.7 mm for men at end-diastole, and 11.8 mm for women and 13.1 mm for men at mid-diastole. LVWT progressively thinned from the base to the apex. Apical LVWT measured on short-axis and long-axis showed a small but statistically significant difference, particularly in Segment 16.
Conclusion: This study provides CCT reference values for LVWT at end-diastole and mid-diastole. Mid-diastolic LVWT was slightly greater than end-diastolic LVWT, with a statistically significant difference. Normal LVWT was greater in men than in women, with regional variations observed in both phases.
目的：利用心脏计算机断层扫描（CCT）研究舒张末期和舒张中期左室壁厚度（LVWT）测量的差异，并建立按阶段、性别和地区分层的LVWT参考值。方法：回顾性纳入2021年至2024年间无心血管疾病史或危险因素的CCT受试者。根据美国心脏协会舒张末期和舒张中期的17段模型，人工测量每段LVWT。区域LVWT计算为相关片段的平均值。结果：共纳入187例患者，平均年龄51±11岁，其中男性77例（41%）。整体LVWT在舒张末期低于舒张中期（5.7±0.8 vs 6.5±0.9 mm， P）。结论：本研究提供了舒张末期和舒张中期LVWT的CCT参考值。舒张中期LVWT略大于舒张末期LVWT，差异有统计学意义。正常LVWT在男性中大于女性，在两个阶段观察到区域差异。
期刊介绍：
The mission of Clinical Imaging is to publish, in a timely manner, the very best radiology research from the United States and around the world with special attention to the impact of medical imaging on patient care. The journal''s publications cover all imaging modalities, radiology issues related to patients, policy and practice improvements, and clinically-oriented imaging physics and informatics. The journal is a valuable resource for practicing radiologists, radiologists-in-training and other clinicians with an interest in imaging. Papers are carefully peer-reviewed and selected by our experienced subject editors who are leading experts spanning the range of imaging sub-specialties, which include:
-Body Imaging-
Breast Imaging-
Cardiothoracic Imaging-
Imaging Physics and Informatics-
Molecular Imaging and Nuclear Medicine-
Musculoskeletal and Emergency Imaging-
Neuroradiology-
Practice, Policy & Education-
Pediatric Imaging-
Vascular and Interventional Radiology
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