1,10-phenanthroline appended novel Schiff base as a selective fluorescent chemosensor for nerve agent stimulants

IF 4.3 2区化学 Q1 SPECTROSCOPY

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2024-12-15 DOI:10.1016/j.saa.2024.125601

Aastha Palta , Priya Thakur , Gulshan Kumar , Priya Vashisht , Vijay Luxami

{"title":"1,10-phenanthroline appended novel Schiff base as a selective fluorescent chemosensor for nerve agent stimulants","authors":"Aastha Palta , Priya Thakur , Gulshan Kumar , Priya Vashisht , Vijay Luxami","doi":"10.1016/j.saa.2024.125601","DOIUrl":null,"url":null,"abstract":"<div><div>A simple, tailor-made, novel chemosensor based on 1,10-phenanthroline Schiff base incorporating N, N-Diethylamino salicylaldehyde (<strong>1</strong>) was designed and synthesized. The sensing ability of chemosensor <strong>1</strong> was tested via colorimetric, UV–Vis and fluorescence spectroscopy. Chemosensor <strong>1</strong> could effectively and specifically detect diethylchlorophosphate (DCP) in acetonitrile displaying naked eye colour change from pale yellow to dark yellow while fluorogenic colour changes from blue to pink fluorescence (365 nm UV lamp irradiation). The spectral changes corroborated the colorimetric results with appreciable bathochromic shifts of 44 and 75 nm in absorption and emission spectra respectively. With DCP, the spectral changes may be attributed to the reaction of the phosphorus group with the hydroxyl group which inhibits the ICT within the molecule. The colorimetric and spectral changes were reversed with the addition of triethylamine (TEA) signifying the reversibility of chemosensor <strong>1.</strong> Significantly, the detection limit of <strong>1</strong> for DCP ions was evaluated to be 4.4 nM with the binding constant value of 1.9 × 10<sup>4</sup> M<sup>−1</sup>. Furthermore, chemosensor <strong>1</strong> showed excellent performance for convenient DCP detection via filter paper fabricated test strips.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"329 ","pages":"Article 125601"},"PeriodicalIF":4.3000,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1386142524017670","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SPECTROSCOPY","Score":null,"Total":0}

引用次数: 0

Abstract

A simple, tailor-made, novel chemosensor based on 1,10-phenanthroline Schiff base incorporating N, N-Diethylamino salicylaldehyde (1) was designed and synthesized. The sensing ability of chemosensor 1 was tested via colorimetric, UV–Vis and fluorescence spectroscopy. Chemosensor 1 could effectively and specifically detect diethylchlorophosphate (DCP) in acetonitrile displaying naked eye colour change from pale yellow to dark yellow while fluorogenic colour changes from blue to pink fluorescence (365 nm UV lamp irradiation). The spectral changes corroborated the colorimetric results with appreciable bathochromic shifts of 44 and 75 nm in absorption and emission spectra respectively. With DCP, the spectral changes may be attributed to the reaction of the phosphorus group with the hydroxyl group which inhibits the ICT within the molecule. The colorimetric and spectral changes were reversed with the addition of triethylamine (TEA) signifying the reversibility of chemosensor 1. Significantly, the detection limit of 1 for DCP ions was evaluated to be 4.4 nM with the binding constant value of 1.9 × 10⁴ M⁻¹. Furthermore, chemosensor 1 showed excellent performance for convenient DCP detection via filter paper fabricated test strips.

Abstract Image

查看原文本刊更多论文

1,10-菲罗啉附加新型希夫碱作为神经毒剂兴奋剂的选择性荧光化学传感器。

设计并合成了基于1,10-菲罗啉希夫碱的N， N-二乙基氨基水杨醛(1)的化学传感器。通过比色法、紫外可见光谱和荧光光谱测试了化学传感器1的传感能力。化学传感器1能有效特异地检测乙腈中的二乙基氯磷酸（DCP），在365 nm紫外灯照射下，肉眼颜色由淡黄色变为深黄色，荧光色由蓝色变为粉红色。光谱变化证实了比色法的结果，吸收光谱和发射光谱分别出现了44 nm和75 nm的明显色移。对于DCP，光谱变化可能是由于磷基团与羟基的反应抑制了分子内的ICT。随着三乙胺（TEA）的加入，比色和光谱变化逆转，表明化学传感器1的可逆性。DCP离子的检出限为4.4 nM，结合常数为1.9 × 104 M-1。此外，化学传感器1表现出优异的性能，可以通过滤纸制作的测试条方便地检测DCP。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 物理-光谱学

CiteScore

8.40

自引率

11.40%

发文量

1364

审稿时长

40 days

期刊介绍： Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (SAA) is an interdisciplinary journal which spans from basic to applied aspects of optical spectroscopy in chemistry, medicine, biology, and materials science. The journal publishes original scientific papers that feature high-quality spectroscopic data and analysis. From the broad range of optical spectroscopies, the emphasis is on electronic, vibrational or rotational spectra of molecules, rather than on spectroscopy based on magnetic moments. Criteria for publication in SAA are novelty, uniqueness, and outstanding quality. Routine applications of spectroscopic techniques and computational methods are not appropriate. Topics of particular interest of Spectrochimica Acta Part A include, but are not limited to: Spectroscopy and dynamics of bioanalytical, biomedical, environmental, and atmospheric sciences, Novel experimental techniques or instrumentation for molecular spectroscopy, Novel theoretical and computational methods, Novel applications in photochemistry and photobiology, Novel interpretational approaches as well as advances in data analysis based on electronic or vibrational spectroscopy.