Prevalence of comorbidities and cardiovascular risk factor management in hand osteoarthritis: a cross-sectional study.

IF 3.2 3区 医学 Q2 RHEUMATOLOGY
Sylvain Mathieu, Françoise Fayet, Marie-Hélène Salembien, Malory Rodere, Martin Soubrier, Anne Tournadre
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引用次数: 0

Abstract

Objectives: To assess the prevalence of comorbidities and management of cardiovascular risk factors according to established guidelines for patients with hand osteoarthritis.

Methods: A cross-sectional study was conducted that included 110 hand osteoarthritis patients. The clinical parameters (pain, function, grip strength, quality of life, sarcopenia, and comorbidities) were assessed along with cardiovascular (CV) risk factors (blood pressure, body mass index, and dyslipidaemia). CV risk was assessed using SCORE2 or SCORE2-OP algorithms. Comparisons of patient characteristics were performed using Student's or chi-squared tests.

Results: Twenty-eight patients were identified with comorbidities, and they tended to be older, male, and with a lower quality of life. The median SCORE2 was 5.1%. SCORE2 was negatively associated with grip strength (r=-0.27, p = 0.02). There was no difference in SCORE2 between hand osteoarthritis patients with (n = 60) and without (n = 50) neuropathic-like pain (5.6 ± 3.7 versus 6.2 ± 3.3%; p = 0.38). Among the 40 patients with an intermediate or high CV risk, 33 (82.5%) were off target for low-density lipoproteins (LDL) level with no lipid-lowering treatment (n = 29) or an insufficient statin treatment (n = 4). Obesity was observed in 24 patients (21.8%) and 30 (27.3%) were overweight. Forty-two patients (41.2%) had blood hypertension (41 systolic and one diastolic patient) despite treatment for 9 patients.

Conclusions: We found an increased CV risk in hand osteoarthritis patients who had an insufficient LDL cholesterol target achievement. Hand osteoarthritis patients appear to have a pro-atherogenic profile. These results suggest that CV risk factors should be assessed in patients with hand osteoarthritis and managed according to recommended guidelines.

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来源期刊
Rheumatology International
Rheumatology International 医学-风湿病学
CiteScore
7.30
自引率
5.00%
发文量
191
审稿时长
16. months
期刊介绍: RHEUMATOLOGY INTERNATIONAL is an independent journal reflecting world-wide progress in the research, diagnosis and treatment of the various rheumatic diseases. It is designed to serve researchers and clinicians in the field of rheumatology. RHEUMATOLOGY INTERNATIONAL will cover all modern trends in clinical research as well as in the management of rheumatic diseases. Special emphasis will be given to public health issues related to rheumatic diseases, applying rheumatology research to clinical practice, epidemiology of rheumatic diseases, diagnostic tests for rheumatic diseases, patient reported outcomes (PROs) in rheumatology and evidence on education of rheumatology. Contributions to these topics will appear in the form of original publications, short communications, editorials, and reviews. "Letters to the editor" will be welcome as an enhancement to discussion. Basic science research, including in vitro or animal studies, is discouraged to submit, as we will only review studies on humans with an epidemological or clinical perspective. Case reports without a proper review of the literatura (Case-based Reviews) will not be published. Every effort will be made to ensure speed of publication while maintaining a high standard of contents and production. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.
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