Hydrodynamics and Aggregation of Nanoparticles with Protein Corona: Effects of Protein Concentration and Ionic Strength (Small 51/2024)

IF 13 2区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Small Pub Date : 2024-12-19 DOI:10.1002/smll.202470377

Hwankyu Lee

引用次数: 0

Abstract

Nanoparticles

Coarse-grained simulations capture the effect of protein concentration on the aggregation and hydrodynamics of nanoparticles coated with protein corona, while all-atom simulations reveal that the influence of ionic strength on particle aggregation depends on the specific proteins involved, in agreement with experiments, which are interpreted by binding free energies, as well as electrostatic and hydrophobic interactions between particles and proteins. More in article number 2403913, Hwankyu Lee.

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来源期刊

Small 工程技术-材料科学：综合

CiteScore

17.70

自引率

3.80%

发文量

1830

审稿时长

2.1 months

期刊介绍： Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments. With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology. Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.