Front Cover: Filling the Gap within 10-Membered Heteroenediynes: Thiaenediyne – An Experimental and Theoretical Study (Eur. J. Org. Chem. 47/2024)

Abstract

The Front Cover illustrates a new member of the heteroenediyne group obtained through Nicholas cyclization. Although thiaenediyne is the least reactive in the Bergman cyclization, its appearance allows the application of NBO analysis to the entire family of benzothiophene-conjugated heteroenediynes, thus substantiating the major role of the heteroatom in the enediyne moiety for the reactivity of enediynes in the Bergman cyclization. More details can be found in the Research Article by I. A. Balova and co-workers (DOI: 10.1002/ejoc.202401127).