ROLE OF RIBONUCLEASES IN THE REGULATION OF IMMUNE RESPONSE.

V Shlyakhovenko, O Samoylenko, A Verbinenko, I Ganusevich
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Abstract

Ribonucleases (RNases) perform many different functions in living systems. They are responsible for the formation and processing of various ribonucleic acids (RNAs), including the messenger RNA and all types of microRNAs, and determine the duration of the existence of different RNAs in the cell and extracellular environment. RNases are ubiquitously expressed in many tissue types. This short review discusses the major types and main functions of RNases, their homeostatic functions, influence of transcription, immunomodulation, and the role of extracellular RNases in the immune defense mechanisms.

核糖核酸酶(RNases)在生命系统中发挥着多种不同的功能。它们负责形成和处理各种核糖核酸(RNA),包括信使 RNA 和所有类型的 microRNA,并决定不同 RNA 在细胞和细胞外环境中的存在时间。RNase 在许多组织类型中普遍表达。这篇简短的综述将讨论 RNases 的主要类型和主要功能、它们的平衡功能、对转录的影响、免疫调节以及细胞外 RNases 在免疫防御机制中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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